SCHEMBL4482993

SCHEMBL4482993

[C](=Cc1cc[c]cc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
APP P05067 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL496414 0.84 APP (0.43) TSHRAPP
SCHEMBL10492226 0.84 APP (0.43) TSHRAPP
SCHEMBL339509 0.84 APP (0.43) TSHRAPP
SCHEMBL9099736 0.70 ACHE (0.42) TSHR
SCHEMBL10535666 0.70 NFE2L2 (0.52) TSHR
SCHEMBL18346350 0.69 TRPA1 (0.57) TSHR
SCHEMBL10742806 0.69 TRPA1 (0.57) TSHR
SCHEMBL48799 0.69 MAOB (0.52)
SCHEMBL920604 0.69 MAOB (0.52)
SCHEMBL49163 0.69 APP (0.67) TSHRAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0975710-B2 POLYMER ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2009-06-10 EP disclosed
EP-0975710-B1 POLYMER ELECTROLUMINESCENT DEVICE KONINKL PHILIPS ELECTRONICS NV (NL) 2003-09-10 EP disclosed
EP-0975710-A1 POLYMER ELECTROLUMINESCENT DEVICE Koninklijke Philips Electronics N.V. (NL) 2000-02-02 EP disclosed
WO-1999021936-A1 POLYMER ELECTROLUMINESCENT DEVICE KONINKLIJKE PHILIPS ELECTRONICS N.V. (NL) 1999-05-06 WO disclosed