SCHEMBL448383

SCHEMBL448383

CCCc1cccc(OP(O)Oc2ccccc2)c1CCC

nearest known ligand 0.45

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 11/20 0.45
LTB4R2 Q9NPC1 10/20 0.45
PPARD Q03181 1/20 0.34
PPARA Q07869 3/20 0.33
HRH1 P35367 1/20 0.33
ALOX5 P09917 1/20 0.33
PTGS2 P35354 1/20 0.33
PPARG P37231 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL449156 0.89 LTB4R (0.44) LTB4RLTB4R2PPARAALOX5PTGS2
SCHEMBL447215 0.82 GABRA1 (0.35) LTB4RLTB4R2HRH1
SCHEMBL10566793 0.82 LTB4R (0.42) LTB4RLTB4R2PPARDPPARAALOX5
SCHEMBL446429 0.79 THRA (0.45) LTB4RLTB4R2PPARAHRH1ALOX5
SCHEMBL28621008 0.79 ALOX5 (0.46) LTB4RLTB4R2PPARAALOX5PTGS2
SCHEMBL8769634 0.78 LTB4R (0.40) LTB4RLTB4R2PPARAPPARG
SCHEMBL11615164 0.78 LTB4R (0.41) LTB4RLTB4R2PPARDPPARAALOX5
SCHEMBL10348809 0.78 PTGS2 (0.53) LTB4RLTB4R2PPARAALOX5PTGS2
SCHEMBL9407312 0.77 LTB4R (0.44) LTB4RLTB4R2PPARDHRH1ALOX5
SCHEMBL11227670 0.77 THRA (0.52) LTB4RLTB4R2PPARAALOX5PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11760952-B2 Lubricant thickener systems from modified tall oil fatty acids, lubricating compositions, and associated methods INGEVITY SOUTH CAROLINA, LLC (US) 2023-09-19 US disclosed
US-20230097718-A1 BIOBASED EXTREME PRESSURE ADDITIVE FOR LUBRICATING COMPOSITIONS AND ASSOCIATED METHODS INGEVITY SOUTH CAROLINA, LLC 2023-03-30 US disclosed
US-20220220408-A1 LUBRICANT THICKENER SYSTEMS FROM MODIFIED TALL OIL FATTY ACIDS, LUBRICATING COMPOSITIONS, AND ASSOCIATED METHODS MAINSTREAM PINE PRODUCTS, LLC 2022-07-14 US disclosed
EP-3562924-B1 LOW VISCOSITY LUBRICATING OIL COMPOSITIONS FOR TURBOMACHINES EXXONMOBIL RES & ENG CO (US) 2022-05-25 EP disclosed
US-10829708-B2 Composition and method for preventing or reducing engine knock and pre-ignition in high compression spark ignition engines EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-11-10 US disclosed
US-10774286-B2 Grease compositions with improved performance and methods of preparing and using the same EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-09-15 US disclosed
EP-3684895-A1 HYDRAULIC OIL COMPOSITIONS WITH IMPROVED HYDROLYTIC AND THERMO-OXIDATIVE STABILITY ExxonMobil Research and Engineering Company (US) 2020-07-29 EP disclosed
WO-2020139333-A1 FORMULATION APPROACH TO EXTEND THE HIGH TEMPERATURE PERFORMANCE OF LITHIUM COMPLEX GREASES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-07-02 WO disclosed
WO-2020131439-A1 GREASE COMPOSITIONS HAVING POLYUREA THICKENERS MADE WITH ISOCYANATE TERMINATED PREPOLYMERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-06-25 WO disclosed
WO-2020131440-A1 GREASE COMPOSITIONS HAVING CALCIUM SULFONATE AND POLYUREA THICKENERS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2020-06-25 WO disclosed
EP-2038385-A1 NOVEL BASE STOCK LUBRICANT BLENDS ExxonMobil Research and Engineering Company (US) 2009-03-25 EP disclosed
US-20080207475-A1 High viscosity novel base stock lubricant viscosity blends HAIGH HEATHER M 2008-08-28 US disclosed
US-20080020954-A1 High viscosity novel base stock lubricant extreme viscosity blends HAIGH HEATHER M 2008-01-24 US disclosed
US-20070298990-A1 High viscosity metallocene catalyst pao novel base stock lubricant blends EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2007-12-27 US disclosed
WO-2007146081-A1 HIGH VISCOSITY NOVEL BASE STOCK LUBRICANT EXTREME VISCOSITY BLENDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-12-21 WO disclosed
WO-2007145923-A1 NOVEL BASE STOCK LUBRICANT BLENDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-12-21 WO disclosed
WO-2007145924-A1 HIGH VISCOSITY METALLOCENE CATALYST PAO NOVEL BASE STOCK LUBRICANT BLENDS EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2007-12-21 WO disclosed
US-20070289897-A1 Novel base stock lubricant blends CAREY JAMES T 2007-12-20 US disclosed
US-20020010103-A1 Lubricating oil composition having excellent thermal stability, extreme pressure resistance and anti-wear performance CHEVRON ORONITE JAPAN LIMITED (JP) 2002-01-24 US disclosed
EP-1148114-A2 Lubricating oil compositions having excellent thermal stabilty, extreme pressure resistance and anti-wear performance Chevron Oronite Japan Limited (JP) 2001-10-24 EP disclosed