Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 9/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30009253 | 0.80 | MAOB (0.40) | — | |
| SCHEMBL30009763 | 0.80 | RIPK1 (0.36) | RAB9A | |
| SCHEMBL30630035 | 0.80 | MAOA (0.34) | ATM | |
| Hydrochloric Acid SCHEMBL31478169 | 0.78 | RIPK1 (0.35) | — | |
| SCHEMBL1843873 | 0.73 | MAOB (0.39) | HTR6RAB9ASMN1; SMN2 | |
| SCHEMBL10287802 | 0.70 | ALDH1A1 (0.38) | — | |
| SCHEMBL30591327 | 0.68 | MAOA (0.35) | SIGMAR1 | |
| SCHEMBL14275214 | 0.65 | MAPT (0.34) | RAB9AATM | |
| SCHEMBL31262995 | 0.64 | SIGMAR1 (0.35) | HTR6CNR1CNR2SIGMAR1 | |
| SCHEMBL30591330 | 0.61 | SLC18A3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7608718-B2 | 4,5-dihydro-1H-pyrazole derivatives having potent CB1-antagonistic activity | SOLVAY PHARMACEUTICALS B.V. (NL) | 2009-10-27 | — | — | US | disclosed |
| US-20070259884-A1 | 4,5-Dihydro-1H-pyrazole derivatives having potent CB1-antagonistic activity | SOLVAY PHARMACEUTICALS B.V. | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259884-A1 | 4,5-Dihydro-1H-pyrazole derivatives having potent CB1-antagonistic activity | CNR1, CNR2, GPR55 | HTR6 269/4885RAB9A 1560/4885CNR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.