SCHEMBL30009253

SCHEMBL30009253

NC(=S)N1CC(c2ccccc2)C=N1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.40
MAOA P21397 5/20 0.34
ALDH1A1 P00352 2/20 0.34
PPARG P37231 1/20 0.34
NCOA2 Q15596 1/20 0.34
NCOA1 Q15788 1/20 0.34
PTGS2 P35354 1/20 0.33
EGFR P00533 2/20 0.32
ERBB2 P04626 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30630035 0.83 MAOA (0.34) MAOBMAOA
SCHEMBL30009763 0.83 RIPK1 (0.36) MAOBMAOAALDH1A1
Hydrochloric Acid SCHEMBL31478169 0.82 RIPK1 (0.35) MAOBMAOAALDH1A1
SCHEMBL4486104 0.80 HTR6 (0.33)
SCHEMBL1843873 0.80 MAOB (0.39) MAOBMAOAALDH1A1PPARGNCOA2
SCHEMBL30591327 0.71 MAOA (0.35) MAOBMAOAALDH1A1
SCHEMBL10287802 0.69 ALDH1A1 (0.38) MAOBMAOAALDH1A1
SCHEMBL14275214 0.68 MAPT (0.34) ALDH1A1
SCHEMBL1843874 0.68 MAOB (0.41) MAOBMAOAALDH1A1PPARGNCOA2
SCHEMBL30591330 0.65 SLC18A3 (0.31) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263367-A1 A FACILE AND ODOR-FREE APPROACH TO CONVERT SULFONYL UREA DERIVATIVES TO CHALCOGENIDE SULFONYL UREA DERIVATIVES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES 2025-08-21 US disclosed
EP-4341246-A1 A FACILE AND ODOR-FREE APPROACH TO CONVERT SULFONYL UREA DERIVATIVES TO CHALCOGENIDE SULFONYL UREA DERIVATIVES The United States of America, as represented by The Secretary, Department of Health and Human Services (US) 2024-03-27 EP disclosed
WO-2022245627-A1 A FACILE AND ODOR-FREE APPROACH TO CONVERT SULFONYL UREA DERIVATIVES TO CHALCOGENIDE SULFONYL UREA DERIVATIVES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2022-11-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263367-A1 A FACILE AND ODOR-FREE APPROACH TO CONVERT SULFONYL UREA DERIVATIVES TO CHALCOGENIDE SULFONYL UREA DERIVATIVES TAS2R40, TAS2R10, TAS2R9 MAOB 3725/4885MAOA 4094/4885ALDH1A1 2544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.