SCHEMBL449587

SCHEMBL449587

COc1ccc(-n2c(CNC(=O)c3ccc4c(c3)OCO4)nc3ccccc3c2=O)cc1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.60
USP2 O75604 1/20 0.59
ALDH1A1 P00352 3/20 0.58
MAPT P10636 3/20 0.58
KDM4E B2RXH2 2/20 0.58
LMNA P02545 1/20 0.58
HPGD P15428 1/20 0.58
GAA P10253 2/20 0.58
TP53 P04637 1/20 0.57
HTR7 P34969 5/20 0.56
PDE10A Q9Y233 2/20 0.53
MEN1 O00255 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52
CYP2C19 P33261 1/20 0.52
KMT2A Q03164 1/20 0.52
RAB9A P51151 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL449634 0.87 ALDH1A1 (0.64) SMN1; SMN2ALDH1A1GAAHTR7PDE10A
SCHEMBL451191 0.85 ALDH1A1 (0.64) SMN1; SMN2ALDH1A1LMNAGAAHTR7
SCHEMBL450020 0.85 HTR7 (0.61) SMN1; SMN2USP2ALDH1A1GAAHTR7
SCHEMBL1552965 0.85 PDE10A (0.62) SMN1; SMN2ALDH1A1GAAHTR7PDE10A
SCHEMBL449655 0.84 POLB (0.61) SMN1; SMN2ALDH1A1GAAHTR7PDE10A
SCHEMBL447996 0.83 HTR7 (0.59) SMN1; SMN2ALDH1A1MAPTGAAHTR7
SCHEMBL452387 0.82 HTR7 (0.59) SMN1; SMN2ALDH1A1GAAHTR7PDE10A
SCHEMBL454025 0.81 ALDH1A1 (0.60) SMN1; SMN2ALDH1A1MAPTKDM4ELMNA
SCHEMBL448566 0.78 ALDH1A1 (0.56) SMN1; SMN2USP2ALDH1A1MAPTKDM4E
SCHEMBL452084 0.77 PDE10A (0.60) ALDH1A1MAPTLMNAGAAHTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841255-B1 RESIN PRODUCTION METHOD AND RESIN PRODUCTION APPARATUS CANON KK (JP) 2020-05-13 EP disclosed
US-10472445-B2 Photocurable composition and method for manufacturing film CANON KABUSHIKI KAISHA (JP) 2019-11-12 US disclosed
EP-2907156-B1 IMPRINTING METHOD AND CURABLE COMPOSITION FOR IMPRINTING CANON KK (JP) 2019-04-10 EP disclosed
EP-2758987-B1 METHOD OF FORMING A FILM CANON KK (JP) 2019-03-20 EP disclosed
US-10233274-B2 Curable composition and patterning method using the same CANON KABUSHIKI KAISHA (JP) 2019-03-19 US disclosed
EP-2760894-B1 PHOTO-CURABLE COMPOSITION AND PATTERNING METHOD USING THE SAME CANON KK (JP) 2018-12-12 EP disclosed
US-9957340-B2 Imprinting method and curable composition for imprinting CANON KABUSHIKI KAISHA (JP) 2018-05-01 US disclosed
US-9961776-B2 Method of producing cured product and method of forming pattern CANON KABUSHIKI KAISHA (JP) 2018-05-01 US disclosed
US-20180039170-A1 NANONIMPRINT LIQUID MATERIAL, METHOD FOR MANUFACTURING NANOIMPRINT LIQUID MATERIAL, METHOD FOR MANUFACTURING CURED PRODUCT PATTERN, METHOD FOR MANUFACTURING OPTICAL COMPONENT, AND METHOD FOR MANUFACTURING CIRCUIT BOARD CANON KABUSHIKI KAISHA (JP) 2018-02-08 US disclosed
US-20170278704-A1 PHOTOCURABLE COMPOSITION, METHOD FOR FORMING A PATTERN, AND METHOD FOR PRODUCING A PHOTOCURED PRODUCT CANON KK (JP) 2017-09-28 US disclosed
WO-2013183467-A1 CURABLE COMPOSITION AND PATTERNING METHOD USING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-12-12 WO disclosed
US-20120164395-A1 MANUFACTURING METHOD FOR PLASTIC MEMBER AND PLASTIC MEMBER CANON KABUSHIKI KAISHA (JP) 2012-06-28 US disclosed
US-20120061864-A1 METHOD FOR MANUFACTURING LENS, APPARATUS FOR MANUFACTURING LENS, AND METHOD FOR MANUFACTURING OPTICAL APPARATUS CANON KABUSHIKI KAISHA (JP) 2012-03-15 US disclosed
EP-2372405-A1 Lens and method for producing lens Canon Kabushiki Kaisha (JP) 2011-10-05 EP disclosed
US-20070275327-A1 PHOTOSENSITIVE RESIN COMPOSITION, RESIST PATTERN FORMING METHOD, SUBSTRATE PROCESSING METHOD, AND DEVICE MANUFACTURING METHOD CANON KABUSHIKI KAISHA (JP) 2007-11-29 US disclosed
US-20050221222-A1 Photosensitive resin composition, resist pattern forming method, substrate processing method, and device manufacturing method CANON KABUSHIKI KAISHA (JP) 2005-10-06 US disclosed
US-6908722-B2 Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition JSR CORPORATION (JP) 2005-06-21 US disclosed
US-6824954-B2 DIHALOMETHYL SULFONYLOXIME COMPOUNDS; FOR EXAMPLE, 2,2-DIFLUORO-2-METHYLACETOPHENONE-O-METHYLSULFONYLOXIME; HEAT STABILITY AND STORAGE STABILITY; SENSITIVE TO FAR ULTRAVIOLET RADIATION OR ELECTRON BEAMS; RESISTS JSR CORPORATION (JP) 2004-11-30 US disclosed
US-20030113658-A1 Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition JSR CORPORATION (JP) 2003-06-19 US disclosed
US-20030113660-A1 Sulfonyloxime compound, and radiation sensitive acid generator, positive type radiation sensitive resin composition and negative type radiation sensitive resin composition using same JSR CORPORATION (JP) 2003-06-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030113658-A1 Acid generator, sulfonic acid, sulfonic acid derivatives and radiation-sensitive resin composition ASIC1, PFAS, RARA SMN1; SMN2 1241/4885USP2 1208/4885ALDH1A1 1216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.