SCHEMBL451060

SCHEMBL451060

[c]1[c]c2c(cc1)-c1ccccc1-2

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
CES2 O00748 1/20 0.32
APAF1 O14727 1/20 0.32
TERT O14746 1/20 0.32
NPC1 O15118 1/20 0.32
PLIN1 O60240 1/20 0.32
TDP2 O95551 1/20 0.32
S1PR4 O95977 1/20 0.32
LMNA P02545 1/20 0.32
PLA2G1B P04054 1/20 0.32
BCHE P06276 1/20 0.32
POLB P06746 1/20 0.32
PTPRC P08575 1/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32
PLCG1 P19174 1/20 0.32
MAOA P21397 1/20 0.32
S1PR1 P21453 1/20 0.32
CES1 P23141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1663621 1.00 KDM4E (0.32) KDM4EMEN1CES2APAF1TERT
SCHEMBL1818666 0.82 MEN1 (0.48) KDM4EMEN1CES2APAF1TERT
SCHEMBL339883 0.71 BACE1 (0.36) LMNAMAPTMAPK1HTT
SCHEMBL4819516 0.69 MEN1 (0.35) KDM4EMEN1CES2APAF1TERT
SCHEMBL195383 0.69 MEN1 (0.35) KDM4EMEN1CES2APAF1TERT
SCHEMBL8493 0.69 MEN1 (0.35) KDM4EMEN1CES2APAF1TERT
SCHEMBL1664629 0.68 KDM4E (0.31) KDM4EMEN1CES2APAF1TERT
SCHEMBL1664166 0.68 KDM4E (0.31) KDM4EMEN1CES2APAF1TERT
SCHEMBL338872 0.67 LMNA (0.38) KDM4ELMNAMAPTHTT
SCHEMBL4388983 0.65 BCHE (0.34) KDM4EMEN1CES2APAF1TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7642357-B2 Iridium complexes TAKASAGO INTERNATIONAL CORPORATION (JP) 2010-01-05 US claimed
US-20090036696-A1 IRIDIUM COMPLEXES TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-02-05 US claimed
US-6946207-B2 Electroconductive device, organic electroluminescence device using the device and process for producing the electroconductive device CANON KABUSHIKI KAISHA (JP) 2005-09-20 US claimed
US-20020135292-A1 Electroconductive device, organic electroluminescence device using the device and process for producing the electroconductive device CANON KABUSHIKI KAISHA (JP) 2002-09-26 US claimed
US-5312707-A Compositions for images RICOH COMPANY, LTD. (JP) 1994-05-17 US claimed
US-12029119-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2024-07-02 US disclosed
CN-110914235-B Terphenyl compound, electrophotographic photoreceptor, and method for producing terphenyl compound 京瓷办公信息系统株式会社 2022-12-09 CN disclosed
CN-113631634-A Polyamic acid composition, polyimide composition, and polyimide molded article 株式会社大阪曹达 2021-11-09 CN disclosed
US-11067909-B2 Terphenyl compound, electrophotographic photosensitive member, and method for producing terphenyl compound KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2021-07-20 US disclosed
US-20200231535-A1 TERPHENYL COMPOUND, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND METHOD FOR PRODUCING TERPHENYL COMPOUND KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-07-23 US disclosed
CN-110914235-A Terphenyl compound, electrophotographic photoreceptor, and method for producing terphenyl compound 京瓷办公信息系统株式会社 2020-03-24 CN disclosed
US-20200052225-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-02-13 US disclosed
US-7642357-B2 Iridium complexes TAKASAGO INTERNATIONAL CORPORATION (JP) 2010-01-05 US disclosed
US-20090221734-A1 RESIN COMPOSITION AND PROCESS FOR THE PRODUCTION THEREOF TEIJIN LIMITED (JP) 2009-09-03 US disclosed
US-20090036696-A1 IRIDIUM COMPLEXES TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-02-05 US disclosed
EP-2006332-A1 RESIN COMPOSITION AND METHOD FOR PRODUCING SAME TEIJIN LIMITED (JP) 2008-12-24 EP disclosed
US-20080075882-A1 PROCESS FOR PRODUCING MOLDED PRINTED MATERIAL, AND MOLDED PRINTED MATERIAL FUJIFILM CORPORATION (JP) 2008-03-27 US disclosed
US-6946207-B2 Electroconductive device, organic electroluminescence device using the device and process for producing the electroconductive device CANON KABUSHIKI KAISHA (JP) 2005-09-20 US disclosed
US-20020135292-A1 Electroconductive device, organic electroluminescence device using the device and process for producing the electroconductive device CANON KABUSHIKI KAISHA (JP) 2002-09-26 US disclosed
US-5312707-A Compositions for images RICOH COMPANY, LTD. (JP) 1994-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090036696-A1 IRIDIUM COMPLEXES HAX1, MLX, H1-0 KDM4E 3265/4885MEN1 1399/4885CES2 2141/4885
US-12029119-B2 Organic electroluminescence element and electronic device LEF1, L1CAM, ESR2 KDM4E 2210/4885MEN1 1680/4885CES2 638/4885
US-11067909-B2 Terphenyl compound, electrophotographic photosensitive member, and method for producing terphenyl compound ABCB1, TERB1, PAH KDM4E 1054/4885MEN1 1946/4885CES2 1209/4885
US-20200052225-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND ELECTRONIC DEVICE LEF1, L1CAM, ESR2 KDM4E 2210/4885MEN1 1680/4885CES2 638/4885
US-20200231535-A1 TERPHENYL COMPOUND, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, AND METHOD FOR PRODUCING TERPHENYL COMPOUND ABCB1, TERB1, PAH KDM4E 1054/4885MEN1 1946/4885CES2 1209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.