SCHEMBL4515328

SCHEMBL4515328

C/C(=N\c1c(C)cccc1C)c1cccc(/C(C)=N/c2c(C)cc(C)cc2Cl)n1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HSP90AA1 P07900 2/20 0.35
ATM Q13315 1/20 0.35
GRIN2D O15399 2/20 0.32
GRIN3B O60391 2/20 0.32
GRIN1 Q05586 2/20 0.32
GRIN2A Q12879 2/20 0.32
GRIN2B Q13224 2/20 0.32
GRIN2C Q14957 2/20 0.32
GRIN3A Q8TCU5 2/20 0.32
SIGMAR1 Q99720 2/20 0.32
RAPGEF4 Q8WZA2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4515332 1.00 MEN1 (0.35) MEN1KMT2AHSP90AA1ATMGRIN2D
SCHEMBL4531342 0.97 KMT2A (0.33) MEN1KMT2AHSP90AA1ATMRAPGEF4
SCHEMBL4531344 0.97 KMT2A (0.33) MEN1KMT2AHSP90AA1ATMRAPGEF4
SCHEMBL30533220 0.96 MEN1 (0.32) MEN1KMT2AHSP90AA1RAPGEF4
SCHEMBL1120701 0.96 KMT2A (0.33) MEN1KMT2AHSP90AA1ATMRAPGEF4
SCHEMBL1120699 0.96 KMT2A (0.33) MEN1KMT2AHSP90AA1ATMRAPGEF4
SCHEMBL29558324 0.96 KMT2A (0.33) MEN1KMT2AHSP90AA1ATMRAPGEF4
SCHEMBL699810 0.94 MEN1 (0.35) MEN1KMT2AHSP90AA1ATMGRIN2D
SCHEMBL699809 0.94 MEN1 (0.35) MEN1KMT2AHSP90AA1ATMGRIN2D
SCHEMBL16654076 0.94 KMT2A (0.33) MEN1KMT2AHSP90AA1ATMRAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11718635-B2 Iron bis(imino) aryl catalysts and methods thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-08 US disclosed
US-11718635-B2 Iron bis(imino) aryl catalysts and methods thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-08 US disclosed
EP-1971577-B1 Process for the preparation of unsymmetric bis(imino) compounds BASELL POLYOLEFINE GMBH (DE) 2014-11-26 EP disclosed
US-8252875-B2 Process for the preparation of unsymmetric bis(imino) compounds BASELL POLYOLEFINE GMBH (DE) 2012-08-28 US disclosed
US-8252875-B2 Process for the preparation of unsymmetric bis(imino) compounds BASELL POLYOLEFINE GMBH (DE) 2012-08-28 US disclosed
US-8252875-B2 Process for the preparation of unsymmetric bis(imino) compounds BASELL POLYOLEFINE GMBH (DE) 2012-08-28 US disclosed
US-20090054609-A1 Process for the Preparation of Unsymmetric Bis(Imino) Compounds BASELL POLYOLEFINE GMBH (DE) 2009-02-26 US disclosed
US-20090054609-A1 Process for the Preparation of Unsymmetric Bis(Imino) Compounds BASELL POLYOLEFINE GMBH (DE) 2009-02-26 US disclosed
US-20090054609-A1 Process for the Preparation of Unsymmetric Bis(Imino) Compounds BASELL POLYOLEFINE GMBH (DE) 2009-02-26 US disclosed
WO-2007080081-A2 PROCESS FOR THE PREPARATION OF UNSYMMETRIC BIS(IMINO) COMPOUNDS BASELL POLYOLEFINE GMBH (DE) 2007-07-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054609-A1 Process for the Preparation of Unsymmetric Bis(Imino) Compounds FHIT, OAT, NONO MEN1 1919/4885KMT2A 1845/4885HSP90AA1 4590/4885
US-11718635-B2 Iron bis(imino) aryl catalysts and methods thereof IDO2, SLC40A1, IDO1 MEN1 1112/4885KMT2A 1685/4885HSP90AA1 3052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.