Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3400235 | 0.76 | ALDH1A1 (0.59) | ALDH1A1TDP1LMNAL3MBTL1KMT2A | |
| SCHEMBL30535903 | 0.74 | ALDH1A1 (0.74) | ALDH1A1TDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL1287837 | 0.74 | ALDH1A1 (0.74) | ALDH1A1TDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL4601208 | 0.74 | MAPT (0.57) | ALDH1A1TDP1LMNAL3MBTL1KMT2A | |
| SCHEMBL30987815 | 0.72 | ALDH1A1 (0.71) | ALDH1A1TDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL29337140 | 0.72 | ALDH1A1 (0.71) | ALDH1A1TDP1L3MBTL1KMT2AMEN1 | |
| Ammonia Solution, Strong SCHEMBL9060371 | 0.72 | ALDH1A1 (0.71) | ALDH1A1TDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL5557695 | 0.71 | ALDH1A1 (0.53) | ALDH1A1TDP1LMNAL3MBTL1KMT2A | |
| SCHEMBL4375599 | 0.71 | ALDH1A1 (0.53) | ALDH1A1TDP1LMNAL3MBTL1KMT2A | |
| SCHEMBL10337930 | 0.71 | ALDH1A1 (0.57) | ALDH1A1TDP1L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11905279-B1 | Benzylidene derivatives of fenobam as anti-inflammatory agents | King Faisal University (SA) | 2024-02-20 | — | — | US | claimed |
| CN-101775020-A | Poly-substituted chromone pyrrole compound and synthetic method and application thereof | UNIV SUN YAT SEN | 2010-07-14 | — | — | CN | claimed |
| US-20090306122-A1 | SUBSTITUTED TETRAHYDROPYRROLOQUINOLINE DERIVATIVES AS KINASE MODULATORS, ESPECIALLY OF TYROSINE AND RAF KINASES | MERCK PATENT GMBH (DE) | 2009-12-10 | — | — | US | claimed |
| EP-1856116-A1 | SUBSTITUTED TETRAHYDROPYRROLOQUINOLINE DERIVATIVES AS KINASE MODULATORS, ESPECIALLY TYROSINE KINASE AND RAF KINASE MODULATORS | Merck Patent GmbH (DE) | 2007-11-21 | — | — | EP | claimed |
| WO-2006094600-A1 | SUBSTITUTED TETRAHYDROPYRROLOQUINOLINE DERIVATIVES AS KINASE MODULATORS, ESPECIALLY TYROSINE KINASE AND RAF KINASE MODULATORS | MERCK PATENT GMBH (DE) | 2006-09-14 | — | — | WO | claimed |
| US-20040023972-A1 | Use of substituted imidazo[1,2-a]-pyridin-, -pyrimidin-and-pyrazin-3-yl-amine derivatives in the preparation of medicaments for inhibiting NOS | GRUENENTHAL GMBH (DE) | 2004-02-05 | — | — | US | claimed |
| EP-1257265-B1 | USE OF 2-PHENYLENE DIAMINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS | BIOAGENCY AG (DE) | 2004-01-21 | — | — | EP | claimed |
| EP-1326613-A1 | USE OF SUBSTITUTED IMIDAZO 1,2-A]PYRIDINE-, IMIDAZO 1,2-A]PYRIMIDINE AND IMIDAZO 1,2-A]PYRAZINE-3-YL-AMINE DERIVATIVES FOR PRODUCING NOS-INHIBITING MEDICAMENTS | Grünenthal GmbH (DE) | 2003-07-16 | — | — | EP | claimed |
| US-20030036532-A1 | Use of 2-phenylene diamine derivatives for the treatment of infections | JOMAA PHARMAKA GMBH (DE) | 2003-02-20 | — | — | US | claimed |
| EP-1257265-A2 | USE OF 2-PHENYLENE DIAMINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS | Jomaa Pharmaka GmbH (DE) | 2002-11-20 | — | — | EP | claimed |
| US-20020086895-A1 | Methods of treating fungal infections | CHU WAI-LAM ALEX (US) | 2002-07-04 | — | — | US | claimed |
| WO-2002030428-A1 | USE OF SUBSTITUTED IMIDAZO[1,2-A]PYRIDINE-, IMIDAZO[1,2-A]PYRIMIDINE AND IMIDAZO[1,2-A]PYRAZINE-3-YL-AMINE DERIVATIVES FOR PRODUCING NOS-INHIBITING MEDICAMENTS | Grünenthal GmbH (DE) | 2002-04-18 | — | — | WO | claimed |
| EP-1005338-A4 | SUBSTITUTED AURONE DERIVATIVES | PHYTERA INC (US) | 2001-11-07 | — | — | EP | claimed |
| WO-2001070026-A2 | 2-PHENYLENEDIAMINE DERIVATIVES AS HERBICIDES | JOMAA PHARMAKA GMBH (DE) | 2001-09-27 | — | — | WO | claimed |
| WO-2001062709-A2 | USE OF 2-PHENYLENE DIAMINE DERIVATIVES FOR THE TREATMENT OF INFECTIONS | JOMAA PHARMAKA GMBH (DE) | 2001-08-30 | — | — | WO | claimed |
| EP-1005338-A1 | SUBSTITUTED AURONE DERIVATIVES | PHYTERA, INC. (US) | 2000-06-07 | — | — | EP | claimed |
| WO-1999004789-A1 | SUBSTITUTED AURONE DERIVATIVES | PHYTERA, INC. (US) | 1999-02-04 | — | — | WO | claimed |
| US-11905279-B1 | Benzylidene derivatives of fenobam as anti-inflammatory agents | King Faisal University (SA) | 2024-02-20 | — | — | US | disclosed |
| EP-1005338-A1 | SUBSTITUTED AURONE DERIVATIVES | PHYTERA, INC. (US) | 2000-06-07 | — | — | EP | disclosed |
| WO-1999004789-A1 | SUBSTITUTED AURONE DERIVATIVES | PHYTERA, INC. (US) | 1999-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030036532-A1 | Use of 2-phenylene diamine derivatives for the treatment of infections | HRH2, ASPH, NQO2 | ALDH1A1 1419/4885TDP1 4770/4885LMNA 3574/4885 |
| US-20020086895-A1 | Methods of treating fungal infections | COXFA4L2, DPM1, ERG28 | ALDH1A1 1149/4885TDP1 2888/4885LMNA 4046/4885 |
| US-11905279-B1 | Benzylidene derivatives of fenobam as anti-inflammatory agents | PTGS1, PTGES2, PTGS2 | ALDH1A1 658/4885TDP1 3486/4885LMNA 3877/4885 |
| US-20090306122-A1 | SUBSTITUTED TETRAHYDROPYRROLOQUINOLINE DERIVATIVES AS KINASE MODULATORS, ESPECIALLY OF TYROSINE AND RAF KINASES | TIE1, FER, RET | ALDH1A1 3078/4885TDP1 1596/4885LMNA 3089/4885 |
| US-20040023972-A1 | Use of substituted imidazo[1,2-a]-pyridin-, -pyrimidin-and-pyrazin-3-yl-amine derivatives in the preparation of medicaments for inhibiting NOS | NOS1, PTGIS, NOS2 | ALDH1A1 3066/4885TDP1 236/4885LMNA 802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.