Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31416868 | 0.91 | THRB (0.42) | LMNATHRBKMT2AMEN1ALDH1A1 | |
| SCHEMBL4531682 | 0.89 | FAAH (0.46) | LMNATHRBKMT2AMEN1ALDH1A1 | |
| SCHEMBL31040363 | 0.89 | FAAH (0.48) | ALDH1A1FAAHNPSR1NAAAHTR2C | |
| SCHEMBL7753303 | 0.87 | FAAH (0.45) | ALDH1A1FAAHNPSR1NAAATSHR | |
| SCHEMBL5404485 | 0.82 | LDHA (0.38) | LMNATHRBKMT2AMEN1ALDH1A1 | |
| SCHEMBL5070359 | 0.82 | LDHA (0.42) | KMT2AMEN1ALDH1A1FAAHNPSR1 | |
| SCHEMBL5804279 | 0.82 | LMNA (0.56) | LMNATHRBKMT2AMEN1ALDH1A1 | |
| SCHEMBL6680472 | 0.81 | ACHE (0.46) | ALDH1A1FAAHNPSR1NAAATSHR | |
| SCHEMBL6681819 | 0.81 | ACHE (0.46) | ALDH1A1FAAHNPSR1NAAATSHR | |
| SCHEMBL10910388 | 0.81 | ACHE (0.46) | ALDH1A1FAAHNPSR1NAAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507764-B2 | Amphiphilic [5:1]- and [3:3]- hexakisadducts of fullerenes | TEGO BIOSCIENCES CORPORATION (US) | 2009-03-24 | — | — | US | disclosed |
| US-20050143327-A1 | Amphiphilic [5:1]- and [3:3]- hexakisadducts of fullerenes | LUNA LABS USA, LLC | 2005-06-30 | — | — | US | disclosed |
| WO-2005037711-A1 | AMPHIPHILIC [5:1]- AND [3:3]- HEXAKISADDUCTS OF FULLERENES | C SIXTY INC. (US) | 2005-04-28 | — | — | WO | disclosed |