Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SCD | O00767 | 1/20 | 0.31 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4538116 | 0.92 | LMNA (0.43) | GPR119LMNAKMT2A | |
| SCHEMBL13586062 | 0.90 | PTPN2 (0.44) | ABL1GPR119NPC1RAB9AHDAC4 | |
| SCHEMBL13586044 | 0.90 | ALDH1A1 (0.37) | ABL1GPR119LMNAKMT2A | |
| SCHEMBL4352709 | 0.86 | HDAC1 (0.33) | ABL1GPR119KMT2A | |
| SCHEMBL4534161 | 0.86 | SCD5 (0.41) | GPR119KMT2ASCDSCD5HRH3 | |
| SCHEMBL4538002 | 0.85 | NPY2R (0.42) | GPR119NAMPTKMT2AHRH3NPY2R | |
| SCHEMBL4533473 | 0.85 | LMNA (0.40) | LMNANAMPT | |
| SCHEMBL4533472 | 0.83 | KMT2A (0.44) | NPC1RAB9AKMT2AHRH3 | |
| SCHEMBL4361277 | 0.83 | MAPK14 (0.40) | LMNANAMPT | |
| SCHEMBL4540129 | 0.82 | ALDH1A1 (0.43) | LMNANAMPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |