SCHEMBL453248

SCHEMBL453248

CC(NC=O)(NC=O)C(=O)O

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.39
TSHR P16473 2/20 0.38
ALDH1A1 P00352 1/20 0.38
ACLY P53396 1/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1187857 0.78
SCHEMBL2495478 0.74
Acetic Acid SCHEMBL10355645 0.72 PKM (0.39) PKMTSHRALDH1A1
SCHEMBL27693427 0.70 NAALAD2 (0.36) PKMTSHRALDH1A1CYP2D6CYP2C19
SCHEMBL27975165 0.70 PKM (0.39) PKMTSHRALDH1A1CYP2D6CYP2C19
SCHEMBL10355717 0.70 PKM (0.39) PKMTSHRALDH1A1CYP2D6CYP2C19
SCHEMBL7322796 0.69
SCHEMBL31647641 0.67
SCHEMBL2482767 0.67
SCHEMBL1812835 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997045510-A1 FOAMING ACIDIC DETERGENT/CLEANSING GEL SALIENT SCIENCE, INC. (US) 1997-12-04 WO claimed
US-20240215608-A1 METHODS OF USING FORMALDEHYDE-FREE ANTIMICROBIAL COMPOSITIONS IN ANIMAL BY-PRODUCT COMPOSITIONS EASTMAN CHEMICAL COMPANY (US) 2024-07-04 US disclosed
US-20240148630-A1 FRAGRANCE DELIVERY COMPOSITIONS TAMINCO BV (BE) 2024-05-09 US disclosed
US-20240074436-A1 ANTIMICROBIAL COMPOSITION FOR ANIMAL FEED TAMINCO BV (BE) 2024-03-07 US disclosed
EP-4319559-A1 METHODS OF USING FORMALDEHYDE-FREE ANTIMICROBIAL COMPOSITIONS IN ANIMAL BY-PRODUCT COMPOSITIONS Eastman Chemical Company (US) 2024-02-14 EP disclosed
EP-4291157-A1 FRAGRANCE DELIVERY COMPOSITIONS Taminco BV (BE) 2023-12-20 EP disclosed
EP-4241758-A2 ANTI-DANDRUFF COMPOSITION L'OREAL (FR) 2023-09-13 EP disclosed
US-20230240292-A1 METHOD FOR GROWING PLANTS TAMINCO BV (BE) 2023-08-03 US disclosed
US-20230210112-A1 METHOD FOR GROWING PLANTS TAMINCO BV (BE) 2023-07-06 US disclosed
WO-2023094606-A1 WATERBORNE ADHESIVE AND/OR SEALANT COMPOSITION SOUDAL (BE) 2023-06-01 WO disclosed
US-20090074683-A1 COMPOSITIONS AND METHODS FOR TREATING KERATINOUS SUBSTRATES L'OREAL (FR) 2009-03-19 US disclosed
US-20090074700-A1 COMPOSITIONS AND METHODS FOR IMPARTING SHINE ONTO HAIR L'OREAL (FR) 2009-03-19 US disclosed
WO-2009036061-A1 COMPOSITIONS AND METHODS FOR TREATING KERATINOUS SUBSTRATES L'OREAL (FR) 2009-03-19 WO disclosed
US-20090071493-A1 COMPOSITIONS AND METHODS FOR CONDITIONING HAIR L'OREAL (FR) 2009-03-19 US disclosed
US-20090071495-A1 COMPOSITIONS AND METHOD FOR SHAPING AND STYLING HAIR L'OREAL (FR) 2009-03-19 US disclosed
US-20090070945-A1 METHOD OF COLORING HAIR L'OREAL (FR) 2009-03-19 US disclosed
US-20080299059-A1 COSMETIC COMPOSITIONS CONTAINING FUNCTIONALIZED METAL-OXIDE LAYERED PIGMENTS AND METHODS OF USE L'OREAL USA PRODUCTS, INC. (FR) 2008-12-04 US disclosed
US-20080299154-A1 COSMETIC HAIR COMPOSITIONS CONTAINING METAL-OXIDE LAYERED PIGMENTS AND METHODS OF USE L'OREAL USA PRODUCTS, INC. (US) 2008-12-04 US disclosed
EP-1997472-A1 Cosmetic hair compositions containing metal-oxide layered pigments and functionalized metal-oxide layered pigments and methods of use L'Oreal (FR) 2008-12-03 EP disclosed
WO-1997045510-A1 FOAMING ACIDIC DETERGENT/CLEANSING GEL SALIENT SCIENCE, INC. (US) 1997-12-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230210112-A1 METHOD FOR GROWING PLANTS TUBB, CBS, BCAT1 PKM 711/4885TSHR 4392/4885ALDH1A1 216/4885
US-20240148630-A1 FRAGRANCE DELIVERY COMPOSITIONS F12, P4HA1, INO80C PKM 1314/4885TSHR 3813/4885ALDH1A1 722/4885
US-20230240292-A1 METHOD FOR GROWING PLANTS PDIA5, PDIA4, PRDX3 PKM 1879/4885TSHR 3379/4885ALDH1A1 1867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.