Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.47 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.47 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.47 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23347632 | 0.90 | TAAR1 (0.47) | HIF1ATAAR1CTSGCMA1PLAAT3 | |
| SCHEMBL1180411 | 0.86 | HIF1A (0.67) | HIF1ATAAR1PLAAT3PLAAT5PLAAT2 | |
| SCHEMBL20563262 | 0.78 | HPGD (0.40) | HIF1APLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL29168148 | 0.77 | NQO2 (0.57) | SMN1; SMN2NPSR1CYP1A2GLACYP3A4 | |
| SCHEMBL4699564 | 0.77 | TAAR1 (0.55) | TAAR1CTSGCMA1PNMTSMN1; SMN2 | |
| SCHEMBL4511567 | 0.76 | L3MBTL1 (0.49) | HIF1ACTSGCMA1PLAAT3PLAAT5 | |
| Trifluoroacetic Acid SCHEMBL30133669 | 0.75 | TAAR1 (0.53) | HIF1ATAAR1CTSGCMA1PNMT | |
| SCHEMBL4589758 | 0.75 | ERN1 (0.44) | HIF1ATAAR1CTSGCMA1CNR1 | |
| SCHEMBL20564483 | 0.74 | MTNR1A (0.50) | HIF1ASMN1; SMN2RAB9A | |
| SCHEMBL15066402 | 0.74 | SMN1; SMN2 (0.42) | TAAR1CTSGCMA1PNMTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090221653-A1 | 7-(2-amino-1-hydroxy-ethyl)-4-hydroxybenzothiazol-2(3H)-one-derivatives as beta2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221653-A1 | 7-(2-amino-1-hydroxy-ethyl)-4-hydroxybenzothiazol-2(3H)-one-derivatives as beta2 adrenoreceptor agonists | ADRB2, ADRB1, ADRA2C | HIF1A 691/4885TAAR1 70/4885CTSG 4348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.