Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4536116 | 0.91 | STAT3 (0.43) | HRH3GRM5HPGDMKNK1MKNK2 | |
| SCHEMBL4533028 | 0.89 | HPGD (0.41) | HRH3ALDH1A1HPGD | |
| SCHEMBL4347903 | 0.88 | GPR119 (0.44) | HRH3 | |
| SCHEMBL4350001 | 0.88 | SLC6A7 (0.46) | ALDH1A1KDM4E | |
| SCHEMBL4525904 | 0.88 | HRH3 (0.40) | HRH3ALDH1A1 | |
| SCHEMBL4540460 | 0.85 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1GRM5HPGDKDM4E | |
| SCHEMBL4532442 | 0.81 | STAT3 (0.43) | HRH3HPGDMKNK1MKNK2 | |
| SCHEMBL4354257 | 0.81 | ROCK2 (0.40) | — | |
| SCHEMBL4355704 | 0.81 | RAB9A (0.46) | HRH3ALDH1A1HPGDKDM4ERAB9A | |
| SCHEMBL4538479 | 0.80 | GPR119 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |