Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 2/20 | 0.32 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13586066 | 0.88 | GPR119 (0.46) | GPR119 | |
| SCHEMBL4347925 | 0.85 | USP30 (0.40) | GPR119PIK3CAKCNH2 | |
| SCHEMBL4538479 | 0.84 | GPR119 (0.41) | GPR119PIK3CAKCNH2CTSC | |
| SCHEMBL4529829 | 0.82 | GPR142 (0.43) | — | |
| SCHEMBL4538191 | 0.82 | TNKS (0.41) | GPR119PIK3CAKCNH2 | |
| SCHEMBL4540933 | 0.81 | CYP11B1 (0.44) | PIK3CA | |
| SCHEMBL4540460 | 0.80 | SMN1; SMN2 (0.43) | PIK3CA | |
| SCHEMBL4356487 | 0.79 | ROCK2 (0.36) | GPR119PIK3CAPIK3CGKCNH2 | |
| SCHEMBL4535866 | 0.77 | GPR119 (0.36) | GPR119PIK3CA | |
| SCHEMBL4535480 | 0.77 | LMNA (0.42) | GPR119PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |