Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 17/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.37 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4540933 | 0.88 | CYP11B1 (0.44) | SCDSCD5NAMPT | |
| SCHEMBL4358178 | 0.85 | GPR119 (0.51) | — | |
| SCHEMBL4347925 | 0.84 | USP30 (0.40) | — | |
| SCHEMBL4538463 | 0.83 | NPY2R (0.39) | CYP2D6 | |
| SCHEMBL4534161 | 0.83 | SCD5 (0.41) | SCDSCD5 | |
| SCHEMBL4534347 | 0.83 | GPR142 (0.32) | GPR142 | |
| SCHEMBL4357683 | 0.83 | POLB (0.48) | — | |
| SCHEMBL4533028 | 0.83 | HPGD (0.41) | — | |
| SCHEMBL4533472 | 0.83 | KMT2A (0.44) | — | |
| SCHEMBL4536658 | 0.82 | GPR119 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |