Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.37 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9131 | 0.92 | TSHR (0.50) | ENPP2TSHRACHEMAPTORAI1 | |
| SCHEMBL28083714 | 0.92 | TSHR (0.50) | ENPP2TSHRACHEMAPTORAI1 | |
| SCHEMBL29392408 | 0.92 | TSHR (0.50) | ENPP2TSHRACHEMAPTORAI1 | |
| Ammonia Solution, Strong SCHEMBL27982010 | 0.90 | TSHR (0.47) | ENPP2TSHRACHEMAPTORAI1 | |
| Water SCHEMBL28105165 | 0.90 | TSHR (0.47) | ENPP2TSHRACHEMAPTORAI1 | |
| Diethylamine SCHEMBL1133302 | 0.82 | LIPG (0.40) | ENPP2TSHRACHEMAPTORAI1 | |
| SCHEMBL2323835 | 0.82 | ENPP2 (0.38) | ENPP2TSHRACHEORAI1ORAI2 | |
| SCHEMBL7032190 | 0.79 | ORAI1 (0.50) | ENPP2TSHRACHEORAI1ORAI2 | |
| Tolyl Boronic Acid SCHEMBL28299771 | 0.78 | CA2 (0.67) | ENPP2TSHRORAI1ORAI2ORAI3 | |
| SCHEMBL12270850 | 0.77 | TSHR (0.45) | ENPP2TSHRACHEORAI1ORAI2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8946476-B2 | Process for the preparation of amino acid derivatives | UCB PHARMA GMBH (DE) | 2015-02-03 | — | — | US | claimed |
| US-8501993-B2 | Processes for the preparation of amides | SYNGENTA LIMITED (GB) | 2013-08-06 | — | — | US | claimed |
| EP-2352721-B1 | NOVEL PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES | UCB PHARMA GMBH (DE) | 2013-03-27 | — | — | EP | claimed |
| US-20120289707-A1 | PROCESS FOR THE PREPARATION OF AMIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-11-15 | — | — | US | claimed |
| US-8227619-B2 | Process for the preparation of amides | SYNGENTA LIMITED (GB) | 2012-07-24 | — | — | US | claimed |
| US-20110263899-A1 | Novel Process for the Preparation of Amino Acid Derivatives | UCB PHARMA GMBH (DE) | 2011-10-27 | — | — | US | claimed |
| US-20110178310-A1 | PROCESS FOR THE PREPARATION OF AMIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-07-21 | — | — | US | claimed |
| US-20110071315-A1 | PROCESSES FOR THE PREPARATION OF AMIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-03-24 | — | — | US | claimed |
| US-11820769-B2 | Triazolopyridin-3-ones or their salts and pharmaceutical compositions comprising the same | YUHAN CORPORATION (KR) | 2023-11-21 | — | — | US | disclosed |
| US-20220024918-A1 | TRIAZOLOPYRIDIN-3-ONES OR THEIR SALTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | YUHAN CORPORATION (KR) | 2022-01-27 | — | — | US | disclosed |
| EP-3894408-A1 | TRIAZOLOPYRIDIN-3-ONES OR THEIR SALTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Yuhan Corporation (KR) | 2021-10-20 | — | — | EP | disclosed |
| US-11091479-B2 | Triazolopyridin-3-ones or their salts and pharmaceutical compositions comprising the same | YUHAN CORPORATION (KR) | 2021-08-17 | — | — | US | disclosed |
| US-11045796-B2 | Process for producing aromatic compound, and palladium complex | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-06-29 | — | — | US | disclosed |
| US-20200223844-A1 | TRIAZOLOPYRIDIN-3-ONES OR THEIR SALTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | YUHAN CORPORATION (KR) | 2020-07-16 | — | — | US | disclosed |
| US-20040161404-A1 | Method for producing coupling compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-08-19 | — | — | US | disclosed |
| US-20040158093-A1 | Process for preparing a biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-08-12 | — | — | US | disclosed |
| EP-1439157-A2 | Method for producing Suzuki coupling compound catalysed by a nickel compound | Sumitomo Chemical Co.,Ltd. (JP) | 2004-07-21 | — | — | EP | disclosed |
| EP-1437354-A1 | 4-OXOQUINOLIZINE ANTIMICROBIALS HAVING 2-PYRIDONE SKELETON AS PARTIAL STRUCTURE | Sato Pharmaceutical Co. Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |
| US-20040024229-A1 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-02-05 | — | — | US | disclosed |
| EP-1346971-A1 | Production method for biarylalanine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11091479-B2 | Triazolopyridin-3-ones or their salts and pharmaceutical compositions comprising the same | VAPB, HDLBP, VAPA | ENPP2 4258/4885TSHR 929/4885ACHE 4153/4885 |
| US-20110071315-A1 | PROCESSES FOR THE PREPARATION OF AMIDES | PAH, CYP3A4, AKR7A2 | ENPP2 1178/4885TSHR 2384/4885ACHE 357/4885 |
| US-11820769-B2 | Triazolopyridin-3-ones or their salts and pharmaceutical compositions comprising the same | VAPB, HDLBP, VAPA | ENPP2 4258/4885TSHR 929/4885ACHE 4153/4885 |
| US-11045796-B2 | Process for producing aromatic compound, and palladium complex | DDT, DRD1, DRD2 | ENPP2 3424/4885TSHR 1067/4885ACHE 2494/4885 |
| US-20040024229-A1 | Production method for biarylalanine | BCAT2, BCAT1, PAH | ENPP2 4186/4885TSHR 1972/4885ACHE 3484/4885 |
| US-20040158093-A1 | Process for preparing a biaryl compound | CYP1B1, REL, CYP2F1 | ENPP2 3832/4885TSHR 1200/4885ACHE 3905/4885 |
| US-20200223844-A1 | TRIAZOLOPYRIDIN-3-ONES OR THEIR SALTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | VAPB, HDLBP, VAPA | ENPP2 4258/4885TSHR 929/4885ACHE 4153/4885 |
| US-20110178310-A1 | PROCESS FOR THE PREPARATION OF AMIDES | H1-5, CYP3A5, CYP2B6 | ENPP2 958/4885TSHR 384/4885ACHE 231/4885 |
| US-20110263899-A1 | Novel Process for the Preparation of Amino Acid Derivatives | BCAT2, DNPEP, NPEPPS | ENPP2 842/4885TSHR 3569/4885ACHE 1598/4885 |
| US-20220024918-A1 | TRIAZOLOPYRIDIN-3-ONES OR THEIR SALTS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | VAPB, HDLBP, VAPA | ENPP2 4258/4885TSHR 929/4885ACHE 4153/4885 |
| US-20120289707-A1 | PROCESS FOR THE PREPARATION OF AMIDES | CHRM2, CHRM1, CYP1B1 | ENPP2 856/4885TSHR 288/4885ACHE 204/4885 |
| US-20040161404-A1 | Method for producing coupling compound | PYM1, MALT1, BET1 | ENPP2 807/4885TSHR 423/4885ACHE 4735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.