Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | OTUD7B | Q6GQQ9 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4351462 | 0.88 | HTR1A (0.40) | NPY2RCLK4HSD17B10CYP1A2ALDH1A1 | |
| SCHEMBL4360506 | 0.87 | GPR119 (0.47) | GPR119USP30 | |
| SCHEMBL4355465 | 0.87 | HTR1A (0.35) | NPY2RCLK4HSD17B10CYP1A2ALDH1A1 | |
| SCHEMBL4535866 | 0.87 | GPR119 (0.36) | CYP2C9HRH3CYP3A4CYP2D6GPR119 | |
| SCHEMBL4356423 | 0.86 | TSHR (0.41) | ALDH1A1HTR1ATSHRLMNASLC9A1 | |
| SCHEMBL4534161 | 0.86 | SCD5 (0.41) | NPY2RALDH1A1KCNH2HRH3OTUD7B | |
| SCHEMBL13586042 | 0.85 | CYP3A4 (0.38) | CLK4HSD17B10CYP1A2ALDH1A1CYP2C9 | |
| SCHEMBL4357683 | 0.85 | POLB (0.48) | ALDH1A1CYP2C9KCNH2ROCK2GPR119 | |
| SCHEMBL4353770 | 0.85 | NPY2R (0.42) | NPY2RCLK4HSD17B10CYP1A2ALDH1A1 | |
| SCHEMBL4355143 | 0.85 | GPR119 (0.46) | NPY2RCYP2C9CYP3A4CYP2D6GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |