Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4538463 | 0.86 | NPY2R (0.39) | TSHRHTR1ASLC9A1ALDH1A1LMNA | |
| SCHEMBL4351462 | 0.82 | HTR1A (0.40) | TSHRHTR1AKMT2AMEN1ALDH1A1 | |
| SCHEMBL4355465 | 0.81 | HTR1A (0.35) | TSHRHTR1ASLC9A1ALDH1A1LMNA | |
| SCHEMBL4360506 | 0.81 | GPR119 (0.47) | — | |
| SCHEMBL13586047 | 0.81 | CYP1A2 (0.43) | TSHRHPGDHTR1AALDH1A1LMNA | |
| SCHEMBL13586042 | 0.80 | CYP3A4 (0.38) | TSHRHTR1ANPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4351631 | 0.79 | ALDH1A1 (0.40) | TSHRHSD11B1HTR1AKMT2AMEN1 | |
| SCHEMBL4361256 | 0.78 | OPRD1 (0.46) | KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4353770 | 0.78 | NPY2R (0.42) | HTR1AALDH1A1 | |
| SCHEMBL4364150 | 0.78 | NAAA (0.35) | HPGDHTR1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |