Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4351462 | 0.94 | HTR1A (0.40) | HTR1AKCNH2HRH3NPY2RGPR119 | |
| SCHEMBL4351631 | 0.88 | ALDH1A1 (0.40) | HTR1AKCNH2HRH3NPY2RALDH1A1 | |
| SCHEMBL4364150 | 0.87 | NAAA (0.35) | HTR1AKCNH2HRH3NPY2RGPR119 | |
| SCHEMBL4538463 | 0.87 | NPY2R (0.39) | HTR1AKCNH2HRH3NPY2RGPR119 | |
| SCHEMBL13586042 | 0.86 | CYP3A4 (0.38) | HTR1AKCNH2HRH3CLK4CYP3A4 | |
| SCHEMBL4350045 | 0.85 | MCHR1 (0.38) | KCNH2GPR119MCHR1CYP2D6 | |
| SCHEMBL4357646 | 0.85 | FKBP1A (0.43) | KDM4EGPR119ALDH1A1MCHR1LMNA | |
| SCHEMBL4353770 | 0.84 | NPY2R (0.42) | HTR1AKCNH2HRH3NPY2RGPR119 | |
| SCHEMBL13586016 | 0.83 | SMN1; SMN2 (0.43) | KCNH2GPR119CYP3A4HSD17B10ALDH1A1 | |
| SCHEMBL13586274 | 0.82 | CTSC (0.36) | HTR1AKCNH2HRH3GPR119MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |