Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 3/20 | 0.42 |
| ▸ | ME2 | P23368 | 2/20 | 0.38 |
| ▸ | ME1 | P48163 | 2/20 | 0.38 |
| ▸ | ME3 | Q16798 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 2/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4538463 | 0.85 | NPY2R (0.39) | NPY2RUSP30CYP2C9CYP3A4HTR1A | |
| SCHEMBL4351462 | 0.85 | HTR1A (0.40) | NPY2RCYP2C9CYP3A4HTR1AKCNH2 | |
| SCHEMBL4355465 | 0.84 | HTR1A (0.35) | NPY2RCYP2C9CYP3A4HTR1AKCNH2 | |
| SCHEMBL4541603 | 0.83 | GPR142 (0.48) | NPY2RCYP2C9CYP3A4CYP1A2MCHR1 | |
| SCHEMBL4351631 | 0.83 | ALDH1A1 (0.40) | NPY2RHTR1AKCNH2HRH3ALDH1A1 | |
| SCHEMBL13586042 | 0.82 | CYP3A4 (0.38) | USP30CYP2C9CYP3A4NAMPTHTR1A | |
| SCHEMBL4360506 | 0.82 | GPR119 (0.47) | USP30GPR119 | |
| SCHEMBL4355143 | 0.82 | GPR119 (0.46) | NPY2RUSP30CYP2C9CYP3A4GPR119 | |
| SCHEMBL4364150 | 0.80 | NAAA (0.35) | NPY2RME2ME1ME3HTR1A | |
| SCHEMBL4532492 | 0.80 | LMNA (0.41) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |