SCHEMBL2779101

SCHEMBL2779101

Nc1cc(Cl)c(O)cc1Cl

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.67
TSHR P16473 8/20 0.60
HSD17B10 Q99714 6/20 0.60
HPGD P15428 4/20 0.60
ALDH1A1 P00352 5/20 0.48
CA1 P00915 4/20 0.48
CA2 P00918 4/20 0.48
CA12 O43570 3/20 0.48
CA7 P43166 3/20 0.48
CA9 Q16790 3/20 0.48
CA14 Q9ULX7 3/20 0.48
MAPK1 P28482 2/20 0.48
ALOX15 P16050 2/20 0.48
ALOX12 P18054 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CYP3A4 P08684 6/20 0.46
TDP1 Q9NUW8 1/20 0.46
TP53 P04637 1/20 0.46
THRB P10828 2/20 0.42
HSP90AA1 P07900 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29408803 1.00 GAA (0.67) GAATSHRHSD17B10HPGDALDH1A1
Hydrochloric Acid SCHEMBL10938578 0.97 GAA (0.63) GAATSHRHSD17B10HPGDALDH1A1
SCHEMBL454590 0.89 TSHR (0.60) GAATSHRHSD17B10HPGDALDH1A1
SCHEMBL29949928 0.89 TSHR (0.60) GAATSHRHSD17B10HPGDALDH1A1
SCHEMBL17000444 0.86 HSD17B10 (0.55) GAATSHRHSD17B10HPGDALDH1A1
SCHEMBL13331360 0.83 HSD17B10 (0.52) GAATSHRHSD17B10HPGDALDH1A1
SCHEMBL29829535 0.83 HSD17B10 (0.52) GAATSHRHSD17B10HPGDALDH1A1
SCHEMBL18382554 0.83 GAA (0.67) GAATSHRHSD17B10HPGDALDH1A1
SCHEMBL26097641 0.83 HSD17B10 (0.60) GAATSHRHSD17B10HPGDALDH1A1
SCHEMBL64092 0.82 GAA (1.00) GAATSHRHSD17B10HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4140998-B1 SUBSTITUTED PYRIDAZINONE COMPOUND AND USE THEREOF HENAN SELKIN BIOMEDICAL TECH CO LTD (CN) 2025-02-12 EP claimed
CN-114163356-B Preparation method of urea pesticide lufenuron 江苏中旗科技股份有限公司 2023-06-06 CN claimed
US-20230167091-A1 SUBSTITUTED PYRIDAZINONE COMPOUND AND USE THEREOF Shandong First Medical University & Shandong Academy Of Medical Sciences (CN) 2023-06-01 US claimed
CN-114163356-A Preparation method of carbamide pesticide lufenuron 江苏中旗科技股份有限公司 2022-03-11 CN claimed
CN-112645936-B Substituted pyridazinone compound and use thereof 山东第一医科大学(山东省医学科学院) 2022-03-01 CN claimed
US-9017726-B2 Biodegradable and thermosensitive poly(organophosphazene)-superparamagnetic nanoparticle complex, preparation method and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2015-04-28 US claimed
US-8586020-B2 Poly(organophosphazene) composition for biomaterials KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-11-19 US claimed
US-20130004455-A1 POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-01-03 US claimed
EP-2540764-A2 Poly(organophosphazene) composition for biomaterials Korea Institute of Science and Technology (KR) 2013-01-02 EP claimed
US-8313771-B2 Phosphazene hydrogels with chemical corss-link, preparation method thereof and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2012-11-20 US claimed
US-20120121517-A1 BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF Korean Institute of Science and Technology of Seoul, Republic of Korea 2012-05-17 US claimed
US-20100297155-A1 PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS-LINK, PREPARATION METHOD THEREOF AND USE THEREOF DECA ITALIA S.R.L. (IT) 2010-11-25 US claimed
EP-2155806-A1 PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS -LINK, PREPARATION METHOD THEREOF AND USE THEREOF Korea Institute of Science and Technology (KR) 2010-02-24 EP claimed
WO-2008153278-A1 PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS -LINK, PREPARATION METHOD THEREOF AND USE THEREOF KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2008-12-18 WO claimed
EP-4140998-B1 SUBSTITUTED PYRIDAZINONE COMPOUND AND USE THEREOF HENAN SELKIN BIOMEDICAL TECH CO LTD (CN) 2025-02-12 EP disclosed
US-11964962-B2 Substituted pyridazinone compound and use thereof Shandong First Medical University & Shandong Academy Of Medical Sciences (CN) 2024-04-23 US disclosed
CN-114163356-B Preparation method of urea pesticide lufenuron 江苏中旗科技股份有限公司 2023-06-06 CN disclosed
EP-0168608-A2 Substituted carboxylic-acid anilides BAYER AG (DE) 1986-01-22 EP disclosed
US-4518804-A INTERMEDIATES FOR INSECTICDAL N-AROYL-N'-PHENYL UREAS THE DOW CHEMICAL COMPANY (US) 1985-05-21 US disclosed
US-4042393-A Silver halide emulsion containing two equivalent type coupler for use in photography KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130004455-A1 POLY(ORGANOPHOSPHAZENE) COMPOSITION FOR BIOMATERIALS PHOSPHO1, PGLS, PHYKPL GAA 425/4885TSHR 4580/4885HSD17B10 2576/4885
US-20120121517-A1 BIODEGRADABLE AND THERMOSENSITIVE POLY(ORGANOPHOSPHAZENE)-SUPERPARAMAGNETIC NANOPARTICLE COMPLEX, PREPARATION METHOD AND USE THEREOF PHOSPHO1, HSPA2, FEM1B GAA 4208/4885TSHR 929/4885HSD17B10 3355/4885
US-11964962-B2 Substituted pyridazinone compound and use thereof THRB, TPO, TSHR GAA 3372/4885TSHR 3/4885HSD17B10 601/4885
US-20100297155-A1 PHOSPHAZENE HYDROGELS WITH CHEMICAL CORSS-LINK, PREPARATION METHOD THEREOF AND USE THEREOF PRUNE1, PHYKPL, PAPSS1 GAA 1314/4885TSHR 3405/4885HSD17B10 982/4885
US-20230167091-A1 SUBSTITUTED PYRIDAZINONE COMPOUND AND USE THEREOF THRB, TPO, TSHR GAA 3372/4885TSHR 3/4885HSD17B10 601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.