SCHEMBL4547683

SCHEMBL4547683

CC(C)CCC(O)C(C)(C)C

nearest known ligand 0.48

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.48
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.31
CA1 P00915 1/20 0.31
MEN1 O00255 1/20 0.30
CYP3A4 P08684 1/20 0.30
ALOX15 P16050 1/20 0.30
KMT2A Q03164 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5185774 0.87 TSHR (0.59) TSHRMAPK1
SCHEMBL5029019 0.87 TSHR (0.59) TSHRMAPK1
SCHEMBL8897375 0.83 TSHR (0.43) TSHRALDH1A1MEN1CYP3A4ALOX15
SCHEMBL5187460 0.80 TSHR (0.46) TSHR
SCHEMBL10026572 0.80 MEN1 (0.33) TSHRALDH1A1MEN1CYP3A4ALOX15
SCHEMBL18471527 0.78 TSHR (0.32) TSHRALDH1A1
SCHEMBL5127678 0.75 TSHR (0.53) TSHR
SCHEMBL7522855 0.74 CETP (0.43) ALDH1A1KMT2A
SCHEMBL7522606 0.74 CETP (0.43) ALDH1A1KMT2A
SCHEMBL7532833 0.74 CETP (0.43) ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240208961-A1 EIF4E INHIBITORS AND USES THEREOF PIC Therapeutics, Inc. 2024-06-27 US disclosed
US-20240208961-A1 EIF4E INHIBITORS AND USES THEREOF PIC Therapeutics, Inc. 2024-06-27 US disclosed
US-20240208961-A1 EIF4E INHIBITORS AND USES THEREOF PIC Therapeutics, Inc. 2024-06-27 US disclosed
WO-2024112894-A1 EIF4E INHIBITORS AND USES THEREOF PIC Therapeutics, Inc. (US) 2024-05-30 WO disclosed
US-20180035705-A1 COMPOSITIONS PROVIDING EXTENDED ENERGY AND METHODS OF USE BLUE DRAGONFLY, INC. (US) 2018-02-08 US disclosed
US-20170080037-A1 Compositions for Regulation and Control of Appetite Therapeutic Solutions LLC 2017-03-23 US disclosed
US-20120196817-A1 METHOD FOR ENHANCING NUTRIENT ABSORPTION WITH ASTRAGALOSIDES NULIV HOLDING INC. (TW) 2012-08-02 US disclosed
US-20120196816-A1 METHOD FOR ENHANCING NUTRIENT ABSORPTION WITH ASTRAGALOSIDES NULIV HOLDING INC. (TW) 2012-08-02 US disclosed
US-8197860-B2 Method for enhancing nutrient absorption with astragalosides NULIV HOLDING INC. (TW) 2012-06-12 US disclosed
US-8168596-B2 Use of cycloartane compounds for treating arthritis NULIV HOLDING INC. (TW) 2012-05-01 US disclosed
US-7959952-B2 topical administration of water insoluble extracts from Astragalus membranaceus comprising cycloartane or astragaloside compounds, to improve skin texture, reducing wrinkles, for ultraviolet radiation protection and antiaging effects NULIV HOLDING INC. (TW) 2011-06-14 US disclosed
US-20100099633-A1 METHOD FOR ENHANCING NUTRIENT ABSORPTION WITH ASTRAGALOSIDES NULIV HOLDING INC. (TW) 2010-04-22 US disclosed
US-20100099637-A1 USE OF CYCLOARTANE COMPOUNDS FOR TREATING ARTHRITIS NULIV HOLDING INC. (TW) 2010-04-22 US disclosed
US-20080057010-A1 METHOD FOR SKIN CARE NULIV SCIENCE LTD. (TW) 2008-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099637-A1 USE OF CYCLOARTANE COMPOUNDS FOR TREATING ARTHRITIS COL2A1, COL1A1, COL14A1 TSHR 2632/4885ALDH1A1 1457/4885MAPK1 2067/4885
US-20100099633-A1 METHOD FOR ENHANCING NUTRIENT ABSORPTION WITH ASTRAGALOSIDES FABP2, SI, SLC10A2 TSHR 1885/4885ALDH1A1 1984/4885MAPK1 3965/4885
US-20240208961-A1 EIF4E INHIBITORS AND USES THEREOF EIF4E, EIF4EBP1, EIF4A1 TSHR 4140/4885ALDH1A1 4776/4885MAPK1 1701/4885
US-20170080037-A1 Compositions for Regulation and Control of Appetite FABP6, TAS2R60, TAS2R40 TSHR 449/4885ALDH1A1 4462/4885MAPK1 2097/4885
US-20120196817-A1 METHOD FOR ENHANCING NUTRIENT ABSORPTION WITH ASTRAGALOSIDES FABP2, SI, SLC10A2 TSHR 1885/4885ALDH1A1 1984/4885MAPK1 3965/4885
US-20080057010-A1 METHOD FOR SKIN CARE CUTA, GLA, BCAS2 TSHR 4017/4885ALDH1A1 2902/4885MAPK1 3067/4885
US-20120196816-A1 METHOD FOR ENHANCING NUTRIENT ABSORPTION WITH ASTRAGALOSIDES FABP2, SI, SLC10A2 TSHR 1885/4885ALDH1A1 1984/4885MAPK1 3965/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.