Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 6/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 6/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL803221 | 0.81 | — | — | |
| SCHEMBL18088055 | 0.80 | CHRM2 (0.34) | ATMDRD2DRD3HTR1ACHRM2 | |
| SCHEMBL10067105 | 0.80 | DRD2 (0.33) | DRD2DRD1 | |
| SCHEMBL23846212 | 0.77 | HTR1D (0.33) | — | |
| SCHEMBL15682090 | 0.77 | ADRA1A (0.35) | ATMDRD2DRD3DRD4ADRA1A | |
| SCHEMBL13328555 | 0.73 | TLR4 (0.34) | ACHE | |
| SCHEMBL15682114 | 0.71 | DRD2 (0.31) | ATMDRD2DRD3DRD4ADRA1A | |
| SCHEMBL18137124 | 0.71 | — | — | |
| SCHEMBL18137136 | 0.71 | — | — | |
| SCHEMBL15682096 | 0.70 | ALDH1A1 (0.35) | DRD2DRD3DRD4ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170362506-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-12-21 | — | — | US | disclosed |
| US-9835890-B2 | Liquid crystal display | MERCK PATENG GMBH (DE) | 2017-12-05 | — | — | US | disclosed |
| US-20170335194-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2017-11-23 | — | — | US | disclosed |
| US-9737854-B2 | Process for the purification of a liquid-crystal mixture | MERCK PATENT GMBH (DE) | 2017-08-22 | — | — | US | disclosed |
| US-9726933-B2 | Liquid-crystal displays and liquid-crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2017-08-08 | — | — | US | disclosed |
| US-9714381-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-07-25 | — | — | US | disclosed |
| US-20170044438-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20170044436-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2017-02-16 | — | — | US | disclosed |
| US-9567285-B2 | Polymerisable compounds and the use thereof in liquid-crystal media and liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-02-14 | — | — | US | disclosed |
| US-9556382-B2 | Polymerisable mixtures and the use thereof in liquid crystal displays | MERCK PATENT GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| US-8043671-B2 | Liquid-crystalline medium and liquid crystal display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-10-25 | — | — | US | disclosed |
| US-20110101270-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-05-05 | — | — | US | disclosed |
| US-20100252777-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-10-07 | — | — | US | disclosed |
| EP-2199362-A2 | Liquid crystalline medium | Merck Patent GmbH (DE) | 2010-06-23 | — | — | EP | disclosed |
| WO-2010057575-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2010-05-27 | — | — | WO | disclosed |
| US-20100108945-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-05-06 | — | — | US | disclosed |
| EP-2182046-A1 | Liquid-crystalline medium and liquid crystal display | Merck Patent GmbH (DE) | 2010-05-05 | — | — | EP | disclosed |
| US-20090309066-A1 | Mixture of polar compounds containing cyclohexane and benzene rings some of which are vinylene-linked, especially containing fluoroalkoxy groups; for electrooptical twisted nematic monitor applications | MERCK PATENT GESELLSCHAFT (DE) | 2009-12-17 | — | — | US | disclosed |
| WO-2009129911-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH, (DE) | 2009-10-29 | — | — | WO | disclosed |
| WO-2008009417-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170044438-A1 | LIQUID-CRYSTALLINE MEDIUM | VIM, COL2A1, COL1A1 | ATM 523/4885DRD2 1605/4885DRD3 1190/4885 |
| US-20090309066-A1 | Mixture of polar compounds containing cyclohexane and benzene rings some of which are vinylene-linked, especially containing fluoroalkoxy groups; for electrooptical twisted nematic monitor applications | VIM, CDH1, LEF1 | ATM 3346/4885DRD2 2150/4885DRD3 1910/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.