Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4429230 | 0.86 | MMP2 (0.35) | OPRM1OPRL1MMP2MMP3MMP9 | |
| SCHEMBL4552557 | 0.78 | OPRM1 (0.34) | CHRM4CHRM5CHRM1OPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL8413869 | 0.71 | OPRM1 (0.35) | OPRM1OPRL1 | |
| SCHEMBL4596592 | 0.66 | MMP13 (0.36) | OPRM1OPRL1CHRM2CHRM3 | |
| SCHEMBL4597523 | 0.65 | NPSR1 (0.32) | CHRM3 | |
| SCHEMBL5179386 | 0.63 | GRIN1 (0.38) | OPRM1CHRM2CHRM3 | |
| SCHEMBL10062784 | 0.63 | CHRM2 (0.57) | CHRM4CHRM5CHRM1OPRM1OPRK1 | |
| SCHEMBL4552097 | 0.63 | CCR5 (0.41) | CHRM4CHRM5CHRM1OPRM1OPRK1 | |
| SCHEMBL4551935 | 0.63 | CCR5 (0.56) | CCR5 | |
| SCHEMBL5266493 | 0.62 | TACR1 (0.55) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088860-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008070758-A1 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2008-06-12 | — | — | WO | disclosed |