Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.32 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.31 |
| ▸ | PDE9A | O76083 | 1/20 | 0.30 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.30 |
| ▸ | EBP | Q15125 | 1/20 | 0.30 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4597510 | 0.78 | KDM4E (0.32) | KDM4EALDH1A1CHRM3MAPTNSD3 | |
| SCHEMBL4596041 | 0.78 | KDM4E (0.32) | KDM4EALDH1A1CHRM3MAPTNSD3 | |
| SCHEMBL4429230 | 0.77 | MMP2 (0.35) | KDM4EPOLBNSD3 | |
| SCHEMBL4596592 | 0.76 | MMP13 (0.36) | GBA1ALDH1A1CHRM3NSD3 | |
| SCHEMBL5179386 | 0.73 | GRIN1 (0.38) | KDM4EALDH1A1CHRM3MAPTNSD3 | |
| Hydrochloric Acid SCHEMBL8413869 | 0.70 | OPRM1 (0.35) | KDM4EALDH1A1MAPT | |
| SCHEMBL4610698 | 0.69 | NSD3 (0.36) | KDM4EALDH1A1CHRM3NSD3 | |
| SCHEMBL4626507 | 0.69 | NSD3 (0.36) | KDM4EALDH1A1CHRM3NSD3 | |
| SCHEMBL4597256 | 0.68 | DRD2 (0.34) | ALDH1A1PDE1C | |
| SCHEMBL4596625 | 0.68 | HTR2C (0.35) | NPSR1KDM4EPOLBALDH1A1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |