Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.40 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557203 | 0.85 | ALDH1A1 (0.42) | CRHBPCRHR2ALDH1A1MAPK1MAPT | |
| SCHEMBL455838 | 0.84 | DCLRE1A (0.43) | CRHBPCRHR2ALDH1A1MAPK1BCL2 | |
| SCHEMBL449516 | 0.82 | ALOX5 (0.39) | MAPTGABRA1GABRB2ALOX5CYP1A2 | |
| SCHEMBL15832277 | 0.82 | CRHBP (0.47) | CRHBPCRHR2ALDH1A1MAPK1MAPT | |
| SCHEMBL28992451 | 0.81 | DCLRE1A (0.47) | ALDH1A1BCL2MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL30380433 | 0.81 | DCLRE1A (0.47) | ALDH1A1BCL2MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL26075795 | 0.80 | CRHBP (0.50) | CRHBPCRHR2ALDH1A1MAPK1MAPT | |
| SCHEMBL31570069 | 0.78 | MAPT (0.53) | ALDH1A1BCL2MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL4888958 | 0.78 | MAPT (0.53) | ALDH1A1BCL2MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL458252 | 0.77 | CYP2A6 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106433185-B | Fluorescent dichroic dye containing 3- (biphenylethynyl) acenaphthene [1,2-b ] quinoxaline, preparation method and application thereof | 大连理工大学 | 2018-01-30 | — | — | CN | disclosed |
| CN-106433185-A | Fluorescent dichroic dye containing 3- (biphenylethynyl) acenaphthene [1,2-b ] quinoxaline, preparation method and application thereof | 大连理工大学 | 2017-02-22 | — | — | CN | disclosed |
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |
| EP-1847544-A1 | NOVEL CONDENSED POLYCYCLIC AROMATIC COMPOUND AND USE THEREOF | National University of Corporation Hiroshima University (JP) | 2007-10-24 | — | — | EP | disclosed |