Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1008034 | 0.78 | MT-CO2 (0.39) | MT-CO2MAPTATMMEN1KMT2A | |
| SCHEMBL1007329 | 0.78 | MT-CO2 (0.51) | MT-CO2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4461545 | 0.71 | ALDH1A1 (0.43) | ALOX15GFERADAM17MAPTAPOBEC3A | |
| SCHEMBL31255669 | 0.71 | ALOX15 (0.40) | ALOX15GFERADAM17MAPTAPOBEC3A | |
| SCHEMBL4332370 | 0.70 | ALDH1A1 (0.52) | ALOX15GFERADAM17MAPTAPOBEC3A | |
| SCHEMBL22746906 | 0.70 | DAGLA (0.41) | ALOX15GFERADAM17ATMALDH1A1 | |
| SCHEMBL5755875 | 0.70 | HPGD (0.44) | ALDH1A1KDM4ERAB9AHDAC3HDAC1 | |
| SCHEMBL28039634 | 0.69 | MAPK1 (0.36) | ALOX15GFERADAM17MAPTAPOBEC3A | |
| SCHEMBL1007280 | 0.69 | HDAC1 (0.42) | ALDH1A1KDM4ERAB9AHTTHDAC1 | |
| SCHEMBL10836381 | 0.68 | ALOX15 (0.50) | ALOX15GFERADAM17MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009144632-A1 | NOVEL COMPOUNDS | PFIZER LIMITED (GB) | 2009-12-03 | — | — | WO | disclosed |