SCHEMBL456616

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL512908	0.81	ACHE (0.42)	ACHEENPP3MAP4K4ARFYN
	SCHEMBL15063921	0.81	ALOX5 (0.50)	MAP4K4PGRESR2
	SCHEMBL458486	0.78	HPGD (0.39)	AKR1C2AKR1C1ACHEENPP3L3MBTL1
	SCHEMBL15063974	0.78	TAAR1 (0.48)	MAP4K4ESR2NOTUM
	SCHEMBL15063944	0.78	RAB9A (0.39)	RAB9AALDH1A1PGRNPC1HPGD
	SCHEMBL15064086	0.78	ALDH1A1 (0.42)	ACHEENPP3MAP4K4ARFYN
	SCHEMBL15063583	0.78	ACHE (0.39)	ACHEENPP3MAP4K4ARFYN
	SCHEMBL15064072	0.78	METAP2 (0.35)	—
	SCHEMBL15063924	0.78	ACHE (0.42)	ACHEENPP3MAP4K4ARFYN
	SCHEMBL15063803	0.77	CYP1A1 (0.47)	CNR1MAP4K4ARCLK4PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.