SCHEMBL4569941

SCHEMBL4569941

Cc1ccc(OC(=O)C(C)(C)C)cc1

nearest known ligand 0.73

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ELANE P08246 16/20 0.73
LMNA P02545 2/20 0.59
ALDH1A1 P00352 2/20 0.47
ATM Q13315 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
GAA P10253 1/20 0.44
PRTN3 P24158 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17882067 0.94 ELANE (0.66) ELANELMNAALDH1A1ATML3MBTL1
SCHEMBL22369614 0.91 ELANE (0.86) ELANEPRTN3
SCHEMBL18882775 0.91 ELANE (0.86) ELANELMNAALDH1A1
SCHEMBL18882774 0.85 ELANE (0.60) ELANELMNAPRTN3
SCHEMBL10483745 0.84 ELANE (1.00) ELANEPRTN3
SCHEMBL13998362 0.84 ELANE (0.76) ELANEPRTN3
SCHEMBL8403640 0.84 ELANE (0.81) ELANEALDH1A1PRTN3
SCHEMBL12727385 0.83 LMNA (0.55) ELANELMNAALDH1A1ATML3MBTL1
SCHEMBL10457691 0.83 ELANE (0.56) ELANE
SCHEMBL11596680 0.83 ELANE (0.73) ELANELMNAPRTN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102408285-B Method for directly aminating benzyl hydrocarbon of methylbenzene derivative UNIV NORTHEAST NORMAL 2013-11-20 CN claimed
CN-119101089-A Oligonucleotide synthesis process of chimeric PMO structure 苏州盛诺维生物科技有限公司 2024-12-10 CN disclosed
CN-118993825-A Method for preparing aromatic thioether derivative by promoting copper-mediated aryl C-H bond vulcanization by organic acid 安徽工业大学 2024-11-22 CN disclosed
US-20240218011-A1 GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF FIREFLY BIO, INC. 2024-07-04 US disclosed
US-11857635-B2 Linker compound, polyethylene glycol-linker conjugate and derivative thereof and polyethylene glycol-linker-drug conjugate JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) 2024-01-02 US disclosed
US-20230364277-A1 E-SELECTIN TARGETING AGENTS GLYCOMIMETICS, INC. (US) 2023-11-16 US disclosed
US-20230265197-A1 MONOCLONAL ANTIBODIES AGAINST HER2 EPITOPE AND METHODS OF USE THEREOF MERSANA THERAPEUTICS, INC. 2023-08-24 US disclosed
US-11680074-B2 Compounds, functionalised dioxaborolane or dioxaborinane derivatives, method for preparing same and uses thereof ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (FR) 2023-06-20 US disclosed
US-11680074-B2 Compounds, functionalised dioxaborolane or dioxaborinane derivatives, method for preparing same and uses thereof ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (FR) 2023-06-20 US disclosed
US-20230167149-A1 CD33 LIGANDS SUITABLE FOR INCORPORATION INTO CARRIERS GLYCOMIMETICS, INC. (US) 2023-06-01 US disclosed
US-20120122679-A1 MESOIONIC PESTICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-05-17 US disclosed
CN-102408285-A Method for directly aminating benzyl hydrocarbon of methylbenzene derivative UNIV NORTHEAST NORMAL 2012-04-11 CN disclosed
US-7342016-B2 Farnesyl protein transferase inhibitors as antitumor agents SCHERING CORPORATION (US) 2008-03-11 US disclosed
US-7244847-B2 Benzimidazole compounds ISIS PHARMACEUTICALS, INC. (US) 2007-07-17 US disclosed
US-6881522-B2 Nonaqueous electrolytic solution and lithium secondary battery UBE INDUSTRIES, LTD. (JP) 2005-04-19 US disclosed
US-20040058251-A1 Nonaqueous electrolytic solution and lithium secondary battery HAMAMOTO TOSHIKAZU (JP) 2004-03-25 US disclosed
EP-1311018-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND LITHIUM SECONDARY BATTERY Ube Industries, Ltd. (JP) 2003-05-14 EP disclosed
EP-0509769-B1 Heterocyclic amides having HLE inhibiting activity ZENECA LTD (GB) 1996-09-11 EP disclosed
US-5521179-A Heterocyclic amides ZENECA LIMITED (GB) 1996-05-28 US disclosed
EP-0509769-A2 Heterocyclic amides having HLE inhibiting activity ZENECA LIMITED (GB) 1992-10-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11680074-B2 Compounds, functionalised dioxaborolane or dioxaborinane derivatives, method for preparing same and uses thereof RDX, XDH, NOX4 ELANE 2138/4885LMNA 1743/4885ALDH1A1 944/4885
US-20240218011-A1 GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF NR3C1, NR3C2, MC2R ELANE 596/4885LMNA 4639/4885ALDH1A1 3778/4885
US-20230167149-A1 CD33 LIGANDS SUITABLE FOR INCORPORATION INTO CARRIERS SIGLEC7, SIGLEC9, ASGR1 ELANE 812/4885LMNA 2576/4885ALDH1A1 522/4885
US-20230364277-A1 E-SELECTIN TARGETING AGENTS SELE, SELPLG, SELP ELANE 13/4885LMNA 2712/4885ALDH1A1 940/4885
US-20120122679-A1 MESOIONIC PESTICIDES CHRM2, CHRM5, CHRM1 ELANE 2461/4885LMNA 3906/4885ALDH1A1 2621/4885
US-20230265197-A1 MONOCLONAL ANTIBODIES AGAINST HER2 EPITOPE AND METHODS OF USE THEREOF ERBB2, EGFR, ERBB3 ELANE 2144/4885LMNA 3887/4885ALDH1A1 4607/4885
US-11857635-B2 Linker compound, polyethylene glycol-linker conjugate and derivative thereof and polyethylene glycol-linker-drug conjugate DCLRE1A, LANCL2, SI ELANE 4482/4885LMNA 1871/4885ALDH1A1 1764/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.