Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 5/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4573572 | 0.86 | GPR119 (0.51) | CHRM4PIK3CDPIK3R1HCRTR2 | |
| SCHEMBL8108991 | 0.86 | GPR119 (0.51) | CHRM4PIK3CDPIK3R1HCRTR2 | |
| SCHEMBL4573090 | 0.84 | CHRM4 (0.45) | CHRM4PIK3CDPIK3R1HCRTR2GRM1 | |
| SCHEMBL4573074 | 0.83 | CTSB (0.45) | CHRM4GRM1 | |
| SCHEMBL4573353 | 0.78 | CTSB (0.42) | GRM1 | |
| SCHEMBL4573182 | 0.78 | PIK3CD (0.41) | CHRM4PIK3CDPIK3R1GRM1 | |
| SCHEMBL8113211 | 0.75 | ROCK2 (0.39) | — | |
| SCHEMBL21551483 | 0.74 | GRM1 (0.48) | CHRM4PIK3CDPIK3R1GRM1CHRM2 | |
| SCHEMBL4573206 | 0.73 | PIK3CD (0.38) | CHRM4PIK3CDPIK3R1GRM1 | |
| SCHEMBL18145739 | 0.73 | CHRM1 (0.53) | CHRM4PIK3CDPIK3R1GRM1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |