Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4307124 | 0.89 | ALDH1A1 (0.54) | ALDH1A1TSHRHSD17B10TDP1CYP3A4 | |
| SCHEMBL4092939 | 0.84 | KDM4E (0.47) | ALDH1A1TSHRHSD17B10TDP1L3MBTL1 | |
| SCHEMBL4533772 | 0.81 | L3MBTL1 (0.62) | ALDH1A1TSHRHSD17B10TDP1L3MBTL1 | |
| SCHEMBL14305809 | 0.80 | ALDH1A1 (0.45) | ALDH1A1TSHRHSD17B10TDP1CYP3A4 | |
| SCHEMBL17400405 | 0.79 | MAOA (0.47) | ALDH1A1TSHRHSD17B10L3MBTL1NPC1 | |
| SCHEMBL4635995 | 0.78 | KDM4E (0.50) | ALDH1A1TSHRHSD17B10TDP1CYP3A4 | |
| SCHEMBL5961843 | 0.78 | CYP3A4 (0.53) | ALDH1A1TSHRHSD17B10TDP1CYP3A4 | |
| SCHEMBL358211 | 0.76 | ALDH1A1 (0.80) | ALDH1A1TSHRHSD17B10TDP1CYP3A4 | |
| SCHEMBL4839351 | 0.76 | ACLY (0.52) | ALDH1A1TSHRHSD17B10TDP1CYP3A4 | |
| SCHEMBL457121 | 0.76 | DYRK1A (0.56) | ALDH1A1TSHRHSD17B10TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |