Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.37 |
| ▸ | TFEB | P19484 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26106629 | 0.84 | ALDH1A1 (0.55) | KMT2AGAAPTGDR2MEN1ALDH1A1 | |
| SCHEMBL2791736 | 0.84 | PTGDR2 (0.42) | KMT2AGAAPTGDR2KDM4EALDH1A1 | |
| SCHEMBL2791739 | 0.82 | PTGDR2 (0.44) | KMT2AGAAPTGDR2KDM4EALDH1A1 | |
| SCHEMBL58004 | 0.81 | PTGS2 (0.52) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL6555180 | 0.81 | ALDH1A1 (0.42) | KMT2AGAAPTGDR2MEN1KDM4E | |
| SCHEMBL30706195 | 0.81 | PTGS2 (0.52) | KMT2AMEN1KDM4EALDH1A1HPGD | |
| SCHEMBL4193610 | 0.81 | NFE2L2 (0.41) | KMT2AGAAPTGDR2MEN1KDM4E | |
| SCHEMBL9054704 | 0.81 | THRB (0.49) | KMT2AGAAPTGDR2KDM4EALDH1A1 | |
| SCHEMBL27562951 | 0.80 | PTGDR2 (0.40) | KMT2AGAAPTGDR2MEN1KDM4E | |
| Benzene SCHEMBL29242020 | 0.79 | PTGS2 (0.55) | KMT2APTGDR2MEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240254093-A1 | GPR35 Agonist Compounds | NXERA PHARMA UK LIMITED (GB) | 2024-08-01 | — | — | US | disclosed |
| CN-110204506-B | CO 2 Synthesis of 1,4-dihydro-2H-3,1-benzoxazine-2-one derivative as C1 source | 常州大学 | 2022-10-28 | — | — | CN | disclosed |
| CN-101066981-B | Non-cyclic nucleoside phosphonate compound and its composition, prepn process and use | SHANGHAI INST MATERIA MEDICA | 2011-10-05 | — | — | CN | disclosed |
| EP-1385988-A4 | SELECTIVE COVALENT-BINDING COMPOUNDS HAVING THERAPEUTIC DIAGNOSTIC AND ANALYTICAL APPLICATIONS | SEMOREX INC (US) | 2008-04-09 | — | — | EP | disclosed |
| US-20040121405-A1 | Selective covalent-binding compounds having therapeutic diagnostic and analytical applications | SEMOREX INC. | 2004-06-24 | — | — | US | disclosed |
| EP-1385988-A2 | SELECTIVE COVALENT-BINDING COMPOUNDS HAVING THERAPEUTIC DIAGNOSTIC AND ANALYTICAL APPLICATIONS | Semorex Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002083708-A2 | SELECTIVE COVALENT-BINDING COMPOUNDS HAVING THERAPEUTIC DIAGNOSTIC AND ANALYTICAL APPLICATIONS | SEMOREX INC. (US) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240254093-A1 | GPR35 Agonist Compounds | GPR35, GPR119, GPR68 | KMT2A 3489/4885GAA 3289/4885PTGDR2 286/4885 |
| US-20040121405-A1 | Selective covalent-binding compounds having therapeutic diagnostic and analytical applications | CD2BP2, HAVCR2, EPCAM | KMT2A 2183/4885GAA 438/4885PTGDR2 4414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.