Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5614997 | 0.89 | MLYCD (0.52) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL14518464 | 0.89 | HDAC4 (0.51) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL17285683 | 0.88 | MAPT (0.71) | ALDH1A1HPGDMAPTTRPM8L3MBTL1 | |
| SCHEMBL28352245 | 0.85 | ALDH1A1 (0.52) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL11210779 | 0.84 | KMT2A (0.56) | ALDH1A1HPGDKMT2AMEN1HDAC1 | |
| SCHEMBL1006489 | 0.83 | NAMPT (0.54) | ALDH1A1HPGDKMT2AMEN1HDAC1 | |
| SCHEMBL3362719 | 0.83 | KMT2A (0.55) | ALDH1A1HPGDKMT2AMEN1HDAC1 | |
| SCHEMBL2220361 | 0.81 | ALDH1A1 (0.55) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL294286 | 0.81 | KMT2A (0.53) | ALDH1A1HPGDKMT2AMEN1MAPT | |
| SCHEMBL17629660 | 0.81 | KMT2A (0.53) | ALDH1A1HPGDKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344942-A | Weakly alkaline cleaning agent | 深圳迪道微电子科技有限公司 | 2024-07-16 | — | — | CN | claimed |
| EP-3310822-B1 | PROCATALYST FOR POLYMERIZATION OF OLEFINS COMPRISING AN AMINOBENZOATE INTERNAL DONOR AND A 1,3-DIETHER INTERNAL DONOR IN A SPECIFIC RATIO | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2023-10-11 | — | — | EP | claimed |
| US-10730971-B2 | Procatalyst for polymerization of olefins comprising an aminobenzoate internal donor and a 1,3-diether internal donor in a specific ratio | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2020-08-04 | — | — | US | claimed |
| US-20180362674-A1 | PROCATALYST FOR POLYMERIZATION OF OLEFINS COMPRISING AN AMINOBENZOATE INTERNAL DONOR AND A 1,3-DIETHER INTERNAL DONOR IN A SPECIFIC RATIO | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2018-12-20 | — | — | US | claimed |
| WO-2015184305-A1 | TREATMENT OF CHRONIC NEUTROPHILIC LEUKEMIA (CNL) AND ATYPICAL CHRONIC MYELOID LEUKEMIA (aCML) BY INHIBITORS OF JAK1 | INCYTE CORPORATION (US) | 2015-12-03 | — | — | WO | claimed |
| US-20070225291-A1 | Substituted Pyrazinone Compounds for the Treatment of Inflammation | PFIZER INC. | 2007-09-27 | — | — | US | claimed |
| EP-1678164-B1 | SUBSTITUTED PYRAZINONE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORP (US) | 2007-04-11 | — | — | EP | claimed |
| EP-1678146-A1 | PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | Pharmacia Corporation (US) | 2006-07-12 | — | — | EP | claimed |
| EP-1678164-A1 | SUBSTITUTED PYRAZINONE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | Pharmacia Corporation (US) | 2006-07-12 | — | — | EP | claimed |
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | claimed |
| WO-2005040133-A1 | PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-05-06 | — | — | WO | claimed |
| WO-2005035527-A1 | SUBSTITUTED PYRAZINONE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORPORATION (US) | 2005-04-21 | — | — | WO | claimed |
| CN-118344942-A | Weakly alkaline cleaning agent | 深圳迪道微电子科技有限公司 | 2024-07-16 | — | — | CN | disclosed |
| EP-3519457-B1 | PROCESS TO PREPARE PROCATALYST FOR POLYMERIZATION OF OLEFINS | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2024-06-12 | — | — | EP | disclosed |
| EP-3596140-B1 | PROCESS FOR PREPARING A PROCATALYST FOR POLYMERIZATION OF OLEFINS | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2024-03-20 | — | — | EP | disclosed |
| EP-3310822-B1 | PROCATALYST FOR POLYMERIZATION OF OLEFINS COMPRISING AN AMINOBENZOATE INTERNAL DONOR AND A 1,3-DIETHER INTERNAL DONOR IN A SPECIFIC RATIO | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2023-10-11 | — | — | EP | disclosed |
| US-4229565-A | BY FORMATION OF THE ACYL CHLORIDE THEN POLYMERIZING TO FORM HIGH MOLECULAR WEIGHT, HEAT RESISTANT POLYESTERS | UNION CARBIDE CORPORATION (US) | 1980-10-21 | — | — | US | disclosed |
| US-4195090-A | ADRENERGIC BLOCKING AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-03-25 | — | — | US | disclosed |
| EP-0005858-A1 | Preparation of polyarylates | UNION CARBIDE CORPORATION (US) | 1979-12-12 | — | — | EP | disclosed |
| US-4115575-A | CARDIOVASCULAR DISORDERS | CIBA-GEIGY CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180362674-A1 | PROCATALYST FOR POLYMERIZATION OF OLEFINS COMPRISING AN AMINOBENZOATE INTERNAL DONOR AND A 1,3-DIETHER INTERNAL DONOR IN A SPECIFIC RATIO | HRH4, EIF4H, MSRB3 | ALDH1A1 1081/4885HPGD 657/4885KMT2A 2876/4885 |
| US-10730971-B2 | Procatalyst for polymerization of olefins comprising an aminobenzoate internal donor and a 1,3-diether internal donor in a specific ratio | HRH4, EIF4H, MSRB3 | ALDH1A1 1081/4885HPGD 657/4885KMT2A 2876/4885 |
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | IL4, ARG2, CASP4 | ALDH1A1 846/4885HPGD 1845/4885KMT2A 3219/4885 |
| US-20070225291-A1 | Substituted Pyrazinone Compounds for the Treatment of Inflammation | CNKSR1, IL1RN, CHUK | ALDH1A1 945/4885HPGD 1046/4885KMT2A 3420/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.