Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 6/20 | 0.54 |
| ▸ | CA12 | O43570 | 12/20 | 0.51 |
| ▸ | CA1 | P00915 | 12/20 | 0.51 |
| ▸ | CA2 | P00918 | 12/20 | 0.51 |
| ▸ | CA4 | P22748 | 12/20 | 0.51 |
| ▸ | CA5A | P35218 | 12/20 | 0.51 |
| ▸ | CA7 | P43166 | 12/20 | 0.51 |
| ▸ | CA9 | Q16790 | 12/20 | 0.51 |
| ▸ | CA13 | Q8N1Q1 | 12/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 12/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4586335 | 0.85 | CCR5 (0.53) | CCR5DRD2 | |
| SCHEMBL4586731 | 0.83 | OPRM1 (0.53) | CCR5DRD2 | |
| SCHEMBL4236512 | 0.82 | CCR5 (0.49) | CCR5 | |
| SCHEMBL4587113 | 0.81 | CCR5 (0.57) | CCR5DRD2 | |
| SCHEMBL4587621 | 0.79 | CCR5 (0.55) | CCR5DRD2 | |
| SCHEMBL4586715 | 0.78 | CCR5 (0.55) | CCR5DRD2 | |
| SCHEMBL4586590 | 0.78 | CCR5 (0.47) | CCR5 | |
| SCHEMBL4586437 | 0.75 | CCR5 (0.47) | CCR5 | |
| SCHEMBL4586726 | 0.75 | CCR5 (0.46) | CCR5DRD2 | |
| SCHEMBL4585633 | 0.74 | CCR5 (0.47) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708703-A4 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC (CA) | 2008-04-09 | — | — | EP | disclosed |
| EP-1708703-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-10-11 | — | — | EP | disclosed |
| WO-2005059107-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2005-06-30 | — | — | WO | disclosed |