Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | PTPRF | P10586 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4590519 | 0.81 | CNR1 (0.39) | CNR1CNR2CYP19A1NQO2LMNA | |
| SCHEMBL3227846 | 0.63 | MTNR1A (0.31) | CYP19A1NQO2MAPTALDH1A1 | |
| SCHEMBL4589655 | 0.63 | — | — | |
| SCHEMBL3110339 | 0.61 | ALDH1A1 (0.40) | CYP19A1NQO2MAPTKDM4EALDH1A1 | |
| SCHEMBL15875350 | 0.60 | ADRA1A (0.35) | CYP19A1NQO2MAPTKDM4EADRA1A | |
| SCHEMBL5722849 | 0.58 | LMNA (0.40) | LMNAKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL2797396 | 0.58 | HTR6 (0.47) | CYP19A1NQO2MAPTKDM4EHTR6 | |
| SCHEMBL3106868 | 0.57 | CYP19A1 (0.44) | CYP19A1NQO2MAPTALDH1A1 | |
| SCHEMBL20549449 | 0.56 | KCNH2 (0.35) | KDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL27877543 | 0.56 | ACHE (0.57) | CYP19A1LMNAMAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008120003-A1 | SUBSTITUTED PIPERIDINES FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | ASTRAZENECA AB (SE) | 2008-10-09 | — | — | WO | disclosed |