Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3613323 | 0.83 | KDM4E (0.39) | PIM2HCAR3KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL4590843 | 0.75 | PTGER4 (0.40) | PTGER4KDM4EALDH1A1GAAMAPT | |
| SCHEMBL13688216 | 0.68 | DYRK1A (0.44) | PTGER4DYRK1APIM1PIM2KDM4E | |
| SCHEMBL3645180 | 0.68 | KDM4E (0.48) | PIM2KDM4EALDH1A1TLR8HSD17B10 | |
| SCHEMBL10102076 | 0.67 | LMNA (0.46) | DYRK1APIM1PIM2KDM4EALDH1A1 | |
| SCHEMBL2638388 | 0.67 | KDM4E (0.51) | PIM1PIM2HCAR3KDM4EALDH1A1 | |
| SCHEMBL17311104 | 0.66 | P2RX7 (0.56) | PIM1PIM2HCAR3KDM4EALDH1A1 | |
| SCHEMBL4590838 | 0.66 | HCAR3 (0.44) | PTGER4PIM1PIM2HCAR3KDM4E | |
| SCHEMBL20929510 | 0.65 | DYRK1A (0.46) | PTGER4DYRK1AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL30138283 | 0.65 | DYRK1A (0.46) | PTGER4DYRK1AKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080146536-A1 | 2-Aminoimidazopyridines for treating neurodegenerative diseases | PHARMACOPEIA, INC. (US) | 2008-06-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080146536-A1 | 2-Aminoimidazopyridines for treating neurodegenerative diseases | ADORA2A, ADORA1, ADORA3 | PTGER4 618/4885DYRK1A 1445/4885PIM1 3856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.