Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14558263 | 0.98 | TSHR (0.48) | TSHRMAPK1MEN1KMT2ANFE2L2 | |
| SCHEMBL17421874 | 0.95 | MEN1 (0.50) | TSHRMAPK1MEN1KMT2ANFE2L2 | |
| SCHEMBL11022579 | 0.89 | CYP1A2 (0.46) | TSHRMAPK1MEN1KMT2ACYP1A2 | |
| SCHEMBL8743871 | 0.88 | CYP1A2 (0.46) | MEN1KMT2ANFE2L2CYP1A2EPHX1 | |
| SCHEMBL11224710 | 0.88 | CYP1A2 (0.46) | MEN1KMT2ANFE2L2CYP1A2EPHX1 | |
| SCHEMBL26999487 | 0.86 | CYP1A2 (0.38) | TSHRMAPK1MEN1KMT2ANFE2L2 | |
| SCHEMBL19619093 | 0.86 | TSHR (0.46) | TSHRMAPK1MEN1KMT2ACYP1A2 | |
| SCHEMBL21938959 | 0.85 | CYP1A2 (0.44) | MEN1KMT2ANFE2L2CYP1A2EPHX1 | |
| SCHEMBL8986251 | 0.85 | NFE2L2 (0.42) | MEN1KMT2ANFE2L2CYP1A2EPHX1 | |
| SCHEMBL15589465 | 0.84 | NFE2L2 (0.40) | NFE2L2CYP1A2EPHX1SMN1; SMN2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828338-B2 | Carbamate derivatives of lactam based N-acylethanolamine acid amidase (NAAA) inhibitors | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-11-28 | — | — | US | disclosed |
| EP-2270069-B1 | CONJUGATED POLYMER, INSOLUBILIZED POLYMER, ORGANIC ELECTROLUMINESCENT DEVICE MATERIAL, COMPOSITION FOR ORGANIC ELECTROLUMINESCENT DEVICE, METHOD FOR PRODUCING POLYMER, ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC EL DISPLAY, AND ORGANIC EL ILLUMINATOR | MITSUBISHI CHEM CORP (JP) | 2017-03-29 | — | — | EP | disclosed |
| US-20160068482-A1 | CARBAMATE DERIVATIVES OF LACTAM BASED N-ACYLETHANOLAMINE ACID AMIDASE (NAAA) INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2016-03-10 | — | — | US | disclosed |
| WO-2014144836-A2 | CARBAMATE DERIVATIVES OF LACTAM BASED N-ACYLETHANOLAMINE ACID AMIDASE (NAAA) INHIBITORS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-09-18 | — | — | WO | disclosed |
| EP-1934215-A1 | ISOTOPICALLY SUBSTITUTED IMIDAZOPYRIDINE DERIVATIVES FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | Nycomed GmbH (DE) | 2008-06-25 | — | — | EP | disclosed |
| EP-1926714-A1 | ISOTOPICALLY SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | Nycomed GmbH (DE) | 2008-06-04 | — | — | EP | disclosed |
| US-20080119510-A1 | Substituted Imidazo [4,5-B] Pyridines As Inhibitors Of Gastric Acid Secretion | ALTANA PHARMA AG (DE) | 2008-05-22 | — | — | US | disclosed |
| EP-1910313-A1 | 6-THIOAMIDE SUBSTITUTED BENZIMIDAZOLES | Nycomed GmbH (DE) | 2008-04-16 | — | — | EP | disclosed |
| WO-2008015196-A1 | 5-,7-BIS-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINES | NYCOMED GMBH (DE) | 2008-02-07 | — | — | WO | disclosed |
| US-7326718-B2 | 8-Substituted imidazopyridines | ALTANA PHARMA AG (DE) | 2008-02-05 | — | — | US | disclosed |
| WO-2005111000-A1 | 7-SUBSTITUTED BENZIMIDAZOLES AND THEIR USE AS INHIBITORS OF GASTRIC ACID SECRETION | ALTANA PHARMA AG (DE) | 2005-11-24 | — | — | WO | disclosed |
| EP-1565465-A1 | 8-SUBSTITUTED IMIDAZOPYRIDINES | ALTANA Pharma AG (DE) | 2005-08-24 | — | — | EP | disclosed |
| WO-2005026164-A1 | PHARMACOLOGICALLY ACTIVE IMIDAZO[4,5-C]PYRIDINES | ALTANA PHARMA AG (DE) | 2005-03-24 | — | — | WO | disclosed |
| US-20040235882-A1 | Amino-substituted imidazopyridines for the treatment of gastrointestial diseases | ALTANA PHARMA AG (DE) | 2004-11-25 | — | — | US | disclosed |
| US-20040235883-A1 | Alkyl-substituted imidazopyridines for the treatment of gastrointestinal disorders | ALTANA PHARMA AG (DE) | 2004-11-25 | — | — | US | disclosed |
| WO-2004046144-A1 | 8-SUBSTITUTED IMIDAZOPYRIDINES | ALTANA PHARMA AG (DE) | 2004-06-03 | — | — | WO | disclosed |
| EP-1419156-A1 | ALKYL-SUBSTITUTED IMIDAZOPYRIDINES FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | ALTANA Pharma AG (DE) | 2004-05-19 | — | — | EP | disclosed |
| EP-1417208-A1 | AMINO-SUBSTITUTED IMIDAZOPYRIDINES FOR THE TREATMENT OF GASTROINTESTINAL DISEASES | ALTANA Pharma AG (DE) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003016310-A1 | ALKYL-SUBSTITUTED IMIDAZOPYRIDINES FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS | ALTANA PHARMA AG (DE) | 2003-02-27 | — | — | WO | disclosed |
| WO-2003014120-A1 | AMINO-SUBSTITUTED IMIDAZOPYRIDINES FOR THE TREATMENT OF GASTROINTESTINAL DISEASES | ALTANA PHARMA AG (DE) | 2003-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160068482-A1 | CARBAMATE DERIVATIVES OF LACTAM BASED N-ACYLETHANOLAMINE ACID AMIDASE (NAAA) INHIBITORS | NAAA, FAAH, FAAH2 | TSHR 4069/4885MAPK1 3901/4885MEN1 1885/4885 |
| US-20040235883-A1 | Alkyl-substituted imidazopyridines for the treatment of gastrointestinal disorders | SLC10A2, ALPI, SI | TSHR 1562/4885MAPK1 1641/4885MEN1 531/4885 |
| US-20080119510-A1 | Substituted Imidazo [4,5-B] Pyridines As Inhibitors Of Gastric Acid Secretion | GIPR, CCKBR, GRPR | TSHR 277/4885MAPK1 322/4885MEN1 1958/4885 |
| US-20040235882-A1 | Amino-substituted imidazopyridines for the treatment of gastrointestial diseases | SLC10A2, ALPI, FABP6 | TSHR 1404/4885MAPK1 2001/4885MEN1 1099/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.