Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10612146 | 0.86 | ALDH1A1 (0.33) | ALDH1A1KDM4ENPC1RAB9AADORA2A | |
| SCHEMBL3452701 | 0.80 | ALDH1A1 (0.35) | ALDH1A1KDM4ENPC1RAB9APOLB | |
| SCHEMBL27517145 | 0.77 | NNMT (0.38) | ALDH1A1ADORA2AHDAC1POLBCYP1A2 | |
| SCHEMBL27773471 | 0.73 | PDE2A (0.31) | — | |
| SCHEMBL95213 | 0.70 | NNMT (0.39) | ALDH1A1KDM4ENPC1RAB9APOLB | |
| SCHEMBL1514960 | 0.70 | POLB (0.44) | ALDH1A1KDM4ENPC1RAB9APOLB | |
| SCHEMBL29839686 | 0.70 | NNMT (0.39) | ALDH1A1KDM4ENPC1RAB9APOLB | |
| SCHEMBL2552279 | 0.68 | IKBKB (0.37) | ALDH1A1LMNATDP1SMN1; SMN2 | |
| SCHEMBL30676086 | 0.68 | IKBKB (0.37) | ALDH1A1LMNATDP1SMN1; SMN2 | |
| SCHEMBL27996748 | 0.66 | LMNA (0.37) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179301-B2 | Dyeing compositions for keratinous fibers containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | claimed |
| US-20030172472-A1 | Oxidaton dyeing composition for keratinous fibres comprising an amphoteric polymer with fatty chain | L'OREAL S.A. (FR) | 2003-09-18 | — | — | US | claimed |
| CN-112469389-B | Amine-based reaction products as functional additives | 汉高股份有限及两合公司 | 2023-06-20 | — | — | CN | disclosed |
| CN-114746069-A | Three-step multi-tone hair dyeing method | 汉高股份有限及两合公司 | 2022-07-12 | — | — | CN | disclosed |
| CN-109310607-B | Use of azomethine-type compounds bearing quinoline derivative units for dyeing keratin fibres | 莱雅公司 | 2022-04-15 | — | — | CN | disclosed |
| US-11129779-B2 | Thickening system in a percarbonate-containing blonding agent | Henkel IP & Holding GmbH (DE) | 2021-09-28 | — | — | US | disclosed |
| US-11052027-B2 | Use of sodium chloride in bleaching agents based on percarbonate for human hair application | HENKEL AG & CO. KGAA (DE) | 2021-07-06 | — | — | US | disclosed |
| WO-2021110306-A1 | MULTI-TONE HAIR DYEING METHOD IN THREE STEPS | HENKEL AG & CO. KGAA (DE) | 2021-06-10 | — | — | WO | disclosed |
| CN-112469389-A | Amine-based reaction products as functional additives | 汉高股份有限及两合公司 | 2021-03-09 | — | — | CN | disclosed |
| US-20200206104-A1 | USE OF SODIUM CHLORIDE IN BLEACHING AGENTS BASED ON PRECARBONATE FOR HUMAN HAIR APPLICATION | HENKEL AG & CO. KGAA (DE) | 2020-07-02 | — | — | US | disclosed |
| US-20200206100-A1 | THICKENING SYSTEM IN A PERCARBONATE-CONTAINING BLONDING AGENT | HENKEL AG & CO. KGAA (DE) | 2020-07-02 | — | — | US | disclosed |
| EP-1189576-A2 | HAIR COMPOSITION COMPRISING AN OXIDASE AND CYCLODEXTRIN | Lion Corporation (JP) | 2002-03-27 | — | — | EP | disclosed |
| CN-1336168-A | Oxidation compositions used for dyeing, long term shaping and bleaching keratin fiber | OREAL (FR) | 2002-02-20 | — | — | CN | disclosed |
| CN-1324608-A | Keratin-fiber oxidation dyeing composition and method of dyeing using said composition | OREAL (FR) | 2001-12-05 | — | — | CN | disclosed |
| EP-1137391-A1 | METHOD FOR TREATING HAIR | Novozymes A/S (DK) | 2001-10-04 | — | — | EP | disclosed |
| WO-2001068042-A1 | METHOD FOR DYEING DRY HAIR | NOVOZYMES A/S (DK) | 2001-09-20 | — | — | WO | disclosed |
| WO-2001000144-A2 | HAIR COMPOSITION COMPRISING AN OXIDASE AND CYCLODEXTRIN | LION CORPORATION (JP) | 2001-01-04 | — | — | WO | disclosed |
| WO-2000078273-A2 | PROCESS FOR PRODUCING A HAIRDYE COMPOSITION | LION CORPORATION (JP) | 2000-12-28 | — | — | WO | disclosed |
| CN-1262923-A | Composit for oxidation dyeing keratin fibre and dyeing method using said composit | OREAL (FR) | 2000-08-16 | — | — | CN | disclosed |
| WO-2000032158-A1 | METHOD FOR TREATING HAIR | NOVOZYMES A/S (DK) | 2000-06-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11129779-B2 | Thickening system in a percarbonate-containing blonding agent | KRT18, DSG1, POLR1C | ALDH1A1 4172/4885KDM4E 3139/4885NPC1 4252/4885 |
| US-20030172472-A1 | Oxidaton dyeing composition for keratinous fibres comprising an amphoteric polymer with fatty chain | KRT18, MB, MDN1 | ALDH1A1 566/4885KDM4E 2014/4885NPC1 4635/4885 |
| US-20200206100-A1 | THICKENING SYSTEM IN A PERCARBONATE-CONTAINING BLONDING AGENT | KRT18, DSG1, POLR1C | ALDH1A1 4172/4885KDM4E 3139/4885NPC1 4252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.