Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | AQP1 | P29972 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596775 | 0.91 | AQP1 (0.40) | DPP4GRM5MEN1KMT2ACYP1A2 | |
| SCHEMBL4596399 | 0.89 | HTR1A (0.34) | MEN1KMT2AAQP1ALDH1A1NPSR1 | |
| SCHEMBL4595082 | 0.86 | AQP1 (0.33) | DPP4SIRT2MEN1KMT2ASLC6A2 | |
| SCHEMBL6047944 | 0.85 | P2RX7 (0.38) | CXCR2SLC6A2SLC6A4 | |
| SCHEMBL4596675 | 0.83 | AQP1 (0.37) | SIRT2AQP1 | |
| SCHEMBL4596984 | 0.82 | AQP1 (0.45) | DPP4SIRT2GRM5CXCR2CYP1A2 | |
| SCHEMBL6047967 | 0.80 | MAPK1 (0.33) | NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL4596728 | 0.78 | SIRT2 (0.52) | SIRT2CXCR2CYP1A2AQP1 | |
| SCHEMBL4596928 | 0.77 | PRKAB2 (0.35) | ALDH1A1MAPTLTB4RLTB4R2 | |
| SCHEMBL4596492 | 0.77 | AQP1 (0.36) | SIRT2AQP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874750-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth Incoporated (US) | 2008-01-09 | — | — | EP | disclosed |