Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4598182 | 0.88 | GRIN1 (0.36) | NSD3GRIN1GRIN2ACHRM2CHRM3 | |
| SCHEMBL5179386 | 0.87 | GRIN1 (0.38) | NSD3GRIN1GRIN2ACHRM2CHRM3 | |
| SCHEMBL4597278 | 0.80 | OPRL1 (0.33) | NSD3GRIN1GRIN2AGRIN2BKDM4E | |
| SCHEMBL4626507 | 0.71 | NSD3 (0.36) | NSD3CHRM2CHRM3KDM4EALDH1A1 | |
| SCHEMBL4610698 | 0.71 | NSD3 (0.36) | NSD3CHRM2CHRM3KDM4EALDH1A1 | |
| SCHEMBL4595948 | 0.70 | BACE1 (0.36) | NSD3GRIN1GRIN2ACHRM2CHRM3 | |
| SCHEMBL4415834 | 0.70 | BACE1 (0.36) | NSD3GRIN1GRIN2ACHRM2CHRM3 | |
| SCHEMBL4597825 | 0.69 | CHRM2 (0.39) | CHRM2CHRM3GRIN2BCHRM1HTR1A | |
| SCHEMBL4596592 | 0.69 | MMP13 (0.36) | NSD3CHRM2CHRM3SLC6A4ALDH1A1 | |
| SCHEMBL4598352 | 0.68 | SLC6A4 (0.41) | PLATSLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |