Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.56 |
| ▸ | FOS | P01100 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | JUN | P05412 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31572667 | 1.00 | LDHA (0.64) | LDHAALOX15ALOX12CA2STAT3 | |
| SCHEMBL4598863 | 1.00 | LDHA (0.64) | LDHAALOX15ALOX12CA2STAT3 | |
| SCHEMBL4598867 | 1.00 | LDHA (0.64) | LDHAALOX15ALOX12CA2STAT3 | |
| SCHEMBL16323169 | 0.87 | ALOX15 (0.71) | LDHAALOX15ALOX12CA2STAT3 | |
| SCHEMBL19337385 | 0.85 | FOS (0.77) | ALOX15ALOX12GABRA1GABRB2FOS | |
| SCHEMBL19342846 | 0.85 | ALOX15 (0.64) | LDHAALOX15ALOX12CA2STAT3 | |
| SCHEMBL16323166 | 0.85 | ALOX15 (0.64) | LDHAALOX15ALOX12CA2STAT3 | |
| SCHEMBL14532804 | 0.85 | FOS (0.77) | ALOX15ALOX12GABRA1GABRB2FOS | |
| SCHEMBL17571985 | 0.85 | GABRA1 (0.54) | LDHAALOX15ALOX12STAT3GABRA1 | |
| SCHEMBL29209157 | 0.85 | LDHA (0.64) | LDHAALOX15ALOX12CA2STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025133657-A1 | BIARYL-TYPE HETEROCYCLIC COMPOUNDS AND ANTI-BACTERIAL USES THEREOF | DEBRECENI EGYETEM (HU) | 2025-06-26 | — | — | WO | disclosed |
| CN-103131734-B | Method for reducing ketone compound by using two alcohol dehydrogenases | ASYMCHEM MEDICAL GROUP TIANJIN INC | 2015-04-22 | — | — | CN | disclosed |
| CN-103131734-A | Method for reducing ketone compound by using two alcohol dehydrogenases | ASYMCHEM MEDICAL GROUP TIANJIN INC | 2013-06-05 | — | — | CN | disclosed |
| US-20080269202-A1 | Novel 2,3-benzodiazepine derivatives and their use as antipsychotic agents | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-10-30 | — | — | US | disclosed |
| WO-2008124075-A1 | NOVEL 2,3-BENZODIAZEPINE DERIVATIVES AND THEIR USE AS ANTIPSYCHOTIC AGENTS | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-10-16 | — | — | WO | disclosed |
| EP-1469079-B1 | Carbonly reductase, polynucleotides comprising DNA encoding the same, methods for producing the same,and methods for producing optically active alcohol utilizing the same | DAICEL CHEM (JP) | 2008-04-09 | — | — | EP | disclosed |
| WO-2007099994-A1 | NOVEL CARBONYL REDUCTASE, GENE FOR THE REDUCTASE, VECTOR, TRANSFORMANT, AND METHOD FOR PRODUCTION OF OPTICALLY ACTIVE ALCOHOL UTILIZING THESE MATERIALS | KANEKA CORPORATION (JP) | 2007-09-07 | — | — | WO | disclosed |
| EP-1469079-A1 | Carbonly reductases, polynucleotides comprising DNA encoding the same, methods for producing the same,and methods for producing optically active alcohol utilizing the same | Daicel Chemical Industries, Ltd. (JP) | 2004-10-20 | — | — | EP | disclosed |
| US-6248573-B1 | SULFONYLATING OR HALOGENATING A (S)-1-PHENYL-2-PROPANOL DERIVATIVE TO PRODUCE (S)-1-PHENYL-2-SUBSTITUTED PROPANE DERIVATIVE; CHEMICAL INTERMEDIATE FOR SYNTHESIS OF ANTIOBESITY DRUG | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |
| US-5902900-A | OPTICAL PURITY, USE AS ANTI-OBESITY AGENTS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1999-05-11 | — | — | US | disclosed |
| US-5679557-A | Process of asymmetrically reducing 1-phenyl-2-oxo-propane derivatives with microorganisms | DAICEL CHEMICAL INDUSTRIES, LIMITED (JP) | 1997-10-21 | — | — | US | disclosed |
| EP-0627397-B1 | Optically active 1-phenyl-2-substituted propane derivatives and methods of producing the same | DAICEL CHEM (JP) | 1997-01-02 | — | — | EP | disclosed |
| US-5508461-A | ANTIOBESITY AGENTS | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0627397-A1 | Optically active 1-phenyl-2-substituted propane derivatives and methods of producing the same | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080269202-A1 | Novel 2,3-benzodiazepine derivatives and their use as antipsychotic agents | GABRA3, GABRB3, GABRA4 | LDHA 4084/4885ALOX15 4111/4885ALOX12 4047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.