Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3218808 | 0.85 | ALDH1A1 (0.43) | ALDH1A1PTGER1TAS2R14LMNASMN1; SMN2 | |
| SCHEMBL4601250 | 0.81 | KEAP1 (0.33) | ALDH1A1PTGER1LMNATSHRTP53 | |
| SCHEMBL15495285 | 0.71 | BMP1 (0.43) | ALDH1A1PTGER1TAS2R14LMNASMN1; SMN2 | |
| SCHEMBL25307327 | 0.70 | MAPT (0.45) | ALDH1A1TAS2R14LMNASMN1; SMN2HTT | |
| SCHEMBL6765985 | 0.70 | ALDH1A1 (0.44) | ALDH1A1TAS2R14LMNASMN1; SMN2HTT | |
| SCHEMBL4601251 | 0.69 | BMP1 (0.35) | ALDH1A1PTGER1TAS2R14LMNASMN1; SMN2 | |
| SCHEMBL12205672 | 0.69 | CNR2 (0.56) | TAS2R14MAPT | |
| SCHEMBL12451189 | 0.66 | CNR2 (0.50) | TAS2R14MAPT | |
| SCHEMBL30701971 | 0.66 | CNR2 (0.46) | TAS2R14LMNAHTTTSHR | |
| SCHEMBL27192066 | 0.66 | CNR2 (0.46) | TAS2R14LMNAHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |