Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 7/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BMP1 | P13497 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4601251 | 0.83 | BMP1 (0.35) | TP53MEN1KMT2APTGER1MAPT | |
| SCHEMBL4600615 | 0.81 | ALDH1A1 (0.36) | TP53PTGER1MAPTALDH1A1MAPK1 | |
| SCHEMBL10921438 | 0.66 | TAS2R14 (0.43) | KEAP1TP53MEN1KMT2ANFE2L2 | |
| SCHEMBL3218808 | 0.64 | ALDH1A1 (0.43) | TP53PTGER1MAPTALDH1A1MAPK1 | |
| SCHEMBL15495285 | 0.61 | BMP1 (0.43) | MEN1KMT2APTGER1MAPTALDH1A1 | |
| SCHEMBL4493208 | 0.58 | MEN1 (0.49) | TP53MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6769019 | 0.56 | TAS2R14 (0.58) | MAPTALDH1A1POLBGAAPKM | |
| SCHEMBL16204380 | 0.56 | CNR2 (0.46) | TP53MAPT | |
| SCHEMBL16197374 | 0.56 | CNR2 (0.46) | TP53MAPT | |
| SCHEMBL14586659 | 0.55 | AGER (0.42) | KEAP1MEN1KMT2ANFE2L2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | claimed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | claimed |