Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3218808 | 0.80 | ALDH1A1 (0.43) | ALDH1A1LMNATP53SMN1; SMN2MAPK1 | |
| SCHEMBL15495285 | 0.77 | BMP1 (0.43) | BMP1ALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL10921438 | 0.71 | TAS2R14 (0.43) | BMP1ALDH1A1LMNATP53MAPT | |
| SCHEMBL6769019 | 0.70 | TAS2R14 (0.58) | ALDH1A1LMNAMAPTTAS2R14GAA | |
| SCHEMBL4600615 | 0.69 | ALDH1A1 (0.36) | ALDH1A1LMNATP53SMN1; SMN2MAPK1 | |
| SCHEMBL15056437 | 0.69 | TAS2R14 (0.40) | BMP1ALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL31551717 | 0.68 | LMNA (0.38) | BMP1ALDH1A1LMNATP53SMN1; SMN2 | |
| SCHEMBL23458589 | 0.67 | GBA1 (0.40) | ALDH1A1KDM4E | |
| SCHEMBL17981098 | 0.67 | RORC (0.44) | ALDH1A1TP53MAPTTHRBTAS2R14 | |
| SCHEMBL10688252 | 0.67 | MEN1 (0.42) | ALDH1A1LMNASMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | claimed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | claimed |