SCHEMBL4600929

SCHEMBL4600929

CC(C)(c1ccccc1)C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
TSHR P16473 2/20 0.52
PDE2A O00408 1/20 0.50
MAPK1 P28482 1/20 0.46
TAAR1 Q96RJ0 1/20 0.42
ALOX15 P16050 1/20 0.42
ESR1 P03372 2/20 0.41
ESR2 Q92731 2/20 0.41
PTPN1 P18031 1/20 0.41
CYP3A4 P08684 1/20 0.41
KCNN4 O15554 3/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA5A P35218 1/20 0.39
CA9 Q16790 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
KIF11 P52732 1/20 0.39
HSD11B1 P28845 1/20 0.38
CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24658569 0.84 ALDH1A1 (0.48) ALDH1A1TSHRPDE2AMAPK1TAAR1
SCHEMBL14707464 0.83 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1TAAR1ALOX15
SCHEMBL96177 0.82 MAPK1 (0.55) ALDH1A1TSHRMAPK1TAAR1ALOX15
SCHEMBL24657857 0.81 ALDH1A1 (0.50) ALDH1A1TSHRMAPK1TAAR1ALOX15
SCHEMBL7864858 0.79 MAPK1 (0.52) ALDH1A1TSHRMAPK1TAAR1ALOX15
SCHEMBL5079313 0.78 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1TAAR1ALOX15
SCHEMBL12339111 0.78 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1TAAR1ALOX15
SCHEMBL20002043 0.78 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1TAAR1ALOX15
SCHEMBL10183591 0.78 PDE2A (0.56) ALDH1A1TSHRPDE2AMAPK1ALOX15
SCHEMBL670252 0.77 MAPK1 (0.50) ALDH1A1TSHRMAPK1TAAR1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12116504-B2 Fluorinated poly(imide-phthalonitrile) adhesive formulations and related methods THE BOEING COMPANY (US) 2024-10-15 US claimed
US-20230392055-A1 FLUORINATED POLY(IMIDE-PHTHALONITRILE) ADHESIVE FORMULATIONS AND RELATED METHODS THE BOEING COMPANY 2023-12-07 US claimed
US-12116504-B2 Fluorinated poly(imide-phthalonitrile) adhesive formulations and related methods THE BOEING COMPANY (US) 2024-10-15 US disclosed
US-20240209013-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-06-27 US disclosed
US-20240023435-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-01-18 US disclosed
US-20230392055-A1 FLUORINATED POLY(IMIDE-PHTHALONITRILE) ADHESIVE FORMULATIONS AND RELATED METHODS THE BOEING COMPANY 2023-12-07 US disclosed
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-26 US disclosed
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230331757-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230337519-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
US-20230337520-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-10-19 US disclosed
EP-1489064-B1 Preparation of fluorinated acetophenones SALTIGO GMBH (DE) 2008-04-16 EP disclosed
US-7301002-B1 Sulfonated polyphenylene polymers SANDIA CORPORATION (US) 2007-11-27 US disclosed
US-7268200-B2 Organosilicate resins as hardmasks for organic polymer dielectrics in fabrication of microelectronic devices DOW GLOBAL TECHNOLOGIES INC. (US) 2007-09-11 US disclosed
US-7268200-B2 Organosilicate resins as hardmasks for organic polymer dielectrics in fabrication of microelectronic devices DOW GLOBAL TECHNOLOGIES INC. (US) 2007-09-11 US disclosed
US-20070185298-A1 Organosilicate resin formulation for use in microelectronic devices DOW GLOBAL TECHNOLOGIES LLC 2007-08-09 US disclosed
US-20070185298-A1 Organosilicate resin formulation for use in microelectronic devices DOW GLOBAL TECHNOLOGIES LLC 2007-08-09 US disclosed
US-7148384-B2 Preparation of fluorinated acetophenones BAYER AKTIENGESELLSCHAFT (DE) 2006-12-12 US disclosed
US-20050043559-A1 Preparation of fluorinated acetophenones LANXESS DEUTSCHLAND GMBH (DE) 2005-02-24 US disclosed
EP-1489064-A1 Preparation of fluorinated acetophenones Bayer Chemicals AG (DE) 2004-12-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050043559-A1 Preparation of fluorinated acetophenones GNPAT, HNF4A, FAH ALDH1A1 184/4885TSHR 2987/4885PDE2A 3903/4885
US-20230331756-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, SSB, LBR ALDH1A1 1702/4885TSHR 2020/4885PDE2A 4750/4885
US-20230337520-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, LPO, LPL ALDH1A1 781/4885TSHR 2071/4885PDE2A 3112/4885
US-20240209013-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, SSB, L1CAM ALDH1A1 419/4885TSHR 1035/4885PDE2A 4311/4885
US-20230331757-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, SSB, L1CAM ALDH1A1 419/4885TSHR 1035/4885PDE2A 4311/4885
US-20230337519-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES SSB, YBX3, LBR ALDH1A1 2953/4885TSHR 851/4885PDE2A 4701/4885
US-20230345811-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OPRD1, L1CAM, OPRM1 ALDH1A1 2748/4885TSHR 1827/4885PDE2A 4771/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.