Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.56 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.56 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.56 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.56 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.56 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.53 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.53 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.53 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.52 |
| ▸ | GSR | P00390 | 1/20 | 0.52 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | RRM1 | P23921 | 1/20 | 0.47 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.47 |
| ▸ | ARG1 | P05089 | 2/20 | 0.47 |
| ▸ | ARG2 | P78540 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9362560 | 1.00 | GRIK1 (0.56) | GRIK1GRIK2SLC1A2SLC1A1DPP7 | |
| SCHEMBL10615527 | 0.98 | GRIK1 (0.57) | GRIK1GRIK2SLC1A2SLC1A1DPP7 | |
| SCHEMBL4385896 | 0.98 | GRIK1 (0.57) | GRIK1GRIK2SLC1A2SLC1A1DPP7 | |
| SCHEMBL27608418 | 0.96 | GRIK1 (0.56) | GRIK1GRIK2SLC1A2SLC1A1DPP7 | |
| SCHEMBL28032333 | 0.96 | GRIK1 (0.56) | GRIK1GRIK2SLC1A2SLC1A1DPP7 | |
| SCHEMBL10286387 | 0.96 | NOD1 (0.52) | GRIK1GRIK2SLC1A2SLC1A1DPP7 | |
| SCHEMBL10285774 | 0.96 | NOD1 (0.52) | GRIK1GRIK2SLC1A2SLC1A1DPP7 | |
| SCHEMBL25635471 | 0.95 | NOD1 (0.55) | GRIK1GRIK2SLC1A2SLC1A1DPP7 | |
| SCHEMBL25227671 | 0.93 | GSR (0.52) | GRIK1GRIK2SLC1A2SLC1A1DPP7 | |
| SCHEMBL22777682 | 0.91 | GRIK1 (0.53) | GRIK1GRIK2SLC1A2SLC1A1DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100196289-A1 | DOUBLE LAYERED OXIDE AND HYDROXIDE PIGMENTS AND METHOD OF THEIR PREPARATION | RELIVIA S.R.L. (IT) | 2010-08-05 | — | — | US | claimed |
| EP-1899421-A1 | DOUBLE LAYERED METAL OXIDE AND HYDROXIDE PIGMENTS AND METHOD OF THEIR PREPARATION | Ghisalberti, Carlo (BR) | 2008-03-19 | — | — | EP | claimed |
| WO-2007083184-A2 | COSMETIC DERMATOLOGY IN ACNEIC AND COMEDOGENIC SKIN | GHISALBERTI CARLO (BR) | 2007-07-26 | — | — | WO | claimed |
| WO-2007083174-A1 | CURATIVE PIGMENTS AND MAKE-UP COMPRISING THEREOF | GHISALBERTI CARLO (BR) | 2007-07-26 | — | — | WO | claimed |
| WO-2006136880-A1 | DOUBLE LAYERED METAL OXIDE AND HYDROXIDE PIGMENTS AND METHOD OF THEIR PREPARATION | GHISALBERTI CARLO (BR) | 2006-12-28 | — | — | WO | claimed |
| EP-0394989-B1 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-12-21 | — | — | EP | claimed |
| EP-0394989-A2 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | claimed |
| US-9637773-B2 | Compounds and methods for detection of enzymes that remove formyl, succinyl, methyl succinyl or myristoyl groups from ε-amino lysine moieties | ENZO LIFE SCIENCES, INC. (US) | 2017-05-02 | — | — | US | disclosed |
| US-20120183948-A1 | Compounds and methods for detection of enzymes that remove formyl, succinyl, methyl succinyl or myristoyl groups from epsilon-amino lysine moieties | ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) | 2012-07-19 | — | — | US | disclosed |
| EP-1852502-B1 | N -ACYL-L-LYSINE-SPECIFIC AMINOACYLASE | AJINOMOTO KK (JP) | 2012-04-18 | — | — | EP | disclosed |
| US-8101661-B2 | Polar hydrophilic prodrugs and non-standard amino acid conjugates of amphetamine and other stimulants and processes for making and using the same | KEMPHARM, INC. (US) | 2012-01-24 | — | — | US | disclosed |
| US-7888079-B2 | microbial N epsilon -acyl-L-lysine-specific degrading and synthesizing enzyme to release a carboxylic acid and L-lysine | AJINOMOTO CO., INC. (JP) | 2011-02-15 | — | — | US | disclosed |
| US-20100292336-A1 | Polar Hydrophilic Prodrugs and Non-Standard Amino Acid Conjugates of Amphetamine and Other Stimulants and Processes for Making and Using the Same | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-11-18 | — | — | US | disclosed |
| EP-1852502-A1 | N -ACYL-L-LYSINE-SPECIFIC AMINOACYLASE | Ajinomoto Co., Inc. (JP) | 2007-11-07 | — | — | EP | disclosed |
| WO-2007083184-A2 | COSMETIC DERMATOLOGY IN ACNEIC AND COMEDOGENIC SKIN | GHISALBERTI CARLO (BR) | 2007-07-26 | — | — | WO | disclosed |
| WO-2007083174-A1 | CURATIVE PIGMENTS AND MAKE-UP COMPRISING THEREOF | GHISALBERTI CARLO (BR) | 2007-07-26 | — | — | WO | disclosed |
| WO-2006136880-A1 | DOUBLE LAYERED METAL OXIDE AND HYDROXIDE PIGMENTS AND METHOD OF THEIR PREPARATION | GHISALBERTI CARLO (BR) | 2006-12-28 | — | — | WO | disclosed |
| EP-0394989-B1 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5274167-A | A N-(meth)acryloyl amino acid amide | BAYER AKTIENGESELLSCHAFT (DE) | 1993-12-28 | — | — | US | disclosed |
| EP-0394989-A2 | Peptide compounds, process for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1990-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120183948-A1 | Compounds and methods for detection of enzymes that remove formyl, succinyl, methyl succinyl or myristoyl groups from epsilon-amino lysine moieties | EMG1, SPR, SHMT1 | GRIK1 1444/4885GRIK2 1792/4885SLC1A2 3690/4885 |
| US-20100196289-A1 | DOUBLE LAYERED OXIDE AND HYDROXIDE PIGMENTS AND METHOD OF THEIR PREPARATION | SOD1, SOD3, GPX4 | GRIK1 1982/4885GRIK2 1156/4885SLC1A2 2095/4885 |
| US-20100292336-A1 | Polar Hydrophilic Prodrugs and Non-Standard Amino Acid Conjugates of Amphetamine and Other Stimulants and Processes for Making and Using the Same | SLC18A2, SLC6A19, SLC6A2 | GRIK1 809/4885GRIK2 791/4885SLC1A2 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.