Sugi Predict

Sugi Predict / Compounds / SCHEMBL460266

SCHEMBL460266

SCHEMBL460266

O=[N+]([O-])c1ccccc1Cc1ccccn1

nearest known ligand 0.63

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.63
▸ KDM4E B2RXH2 1/20 0.63
▸ TSHR P16473 1/20 0.51
▸ KMT2A Q03164 3/20 0.49
▸ MEN1 O00255 2/20 0.49
▸ POLB P06746 2/20 0.49
▸ PKM P14618 2/20 0.48
▸ HPGD P15428 1/20 0.47
▸ MET P08581 1/20 0.47
▸ AR P10275 1/20 0.47
▸ CTSB P07858 1/20 0.46
▸ NPC1 O15118 2/20 0.44
▸ RAB9A P51151 2/20 0.44
▸ PDE10A Q9Y233 1/20 0.44
▸ LMNA P02545 2/20 0.43
▸ GAA P10253 1/20 0.43
▸ MAPT P10636 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ SMN1; SMN2 Q16637 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1917133 0.88 ALDH1A1 (0.54) ALDH1A1KDM4ETSHRKMT2AMEN1
SCHEMBL5159572 0.83 CYP1A2 (0.52) ALDH1A1KDM4EKMT2AMEN1POLB
SCHEMBL29693715 0.83 CYP1A2 (0.52) ALDH1A1KDM4EKMT2AMEN1POLB
SCHEMBL1750770 0.83 PKM (0.58) ALDH1A1KDM4ETSHRKMT2AMEN1
SCHEMBL9636136 0.82 L3MBTL1 (0.48) ALDH1A1KDM4ETSHRPOLBPKM
SCHEMBL28562911 0.82 KDM4E (0.48) ALDH1A1KDM4EKMT2AMEN1POLB
SCHEMBL17728707 0.81 ALDH1A1 (0.48) ALDH1A1KDM4ETSHRKMT2APOLB
SCHEMBL301933 0.80 ALDH1A1 (0.69) ALDH1A1TSHRKMT2AMEN1HPGD
SCHEMBL11425242 0.79 ALDH1A1 (0.56) ALDH1A1TSHRPOLBLMNAMAPT
SCHEMBL11776814 0.79 MAPT (0.63) ALDH1A1KDM4EKMT2AMEN1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3290021-A1 COMPOSTION FOR TOPICAL APPLICATION COMPRISING A PHOTOCHROMIC AGENT Unilever N.V. (NL) 2018-03-07 — — EP claimed
EP-1555009-B1 Skin make-up composition OREAL (FR) 2010-07-14 — — EP claimed
CN-100456398-C Electrolyte for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORP (JP) 2009-01-28 — — CN claimed
WO-2008078025-A2 MAKE-UP COMPOSITION FOR THE SKIN L'OREAL (FR) 2008-07-03 — — WO claimed
US-20070183992-A1 Cosmetic composition comprising porous particles incorporating optically active substances L'ORÉAL 2007-08-09 — — US claimed
US-20070029529-A1 Electrolytic solution for driving electrolytic capacitor and electrolytic capacitor KOMATSU AKIHIKO 2007-02-08 — — US claimed
EP-1660024-A1 COSMETIC COMPOSITION COMPRISING POROUS PARTICLES INCORPORATING OPTICALLY ACTIVE SUBSTANCES L'OREAL (FR) 2006-05-31 — — EP claimed
US-20050175562-A1 crosslinked organopolysiloxane having dimethylvinylsiloxy end groups and a methylhydropolysiloxane having trimethylsiloxy end groups; water, oil, water soluble sovlent as liquid binder; and goniochromatic / photochromic or fluorescent coloring agents; cosmetic L'OREAL S.A. (FR) 2005-08-11 — — US claimed
EP-1555009-A1 Skin make-up composition L'OREAL (FR) 2005-07-20 — — EP claimed
WO-2005011622-A1 COSMETIC COMPOSITION COMPRISING POROUS PARTICLES INCORPORATING OPTICALLY ACTIVE SUBSTANCES L'OREAL (FR) 2005-02-10 — — WO claimed
US-20040245105-A1 Electrolyte solution for driving electrolytic capacitor and electrolytic capacitor RUBYCON CORPORATION (JP) 2004-12-09 — — US claimed
CN-1529892-A Electrolyte for driving electrolytic capacitor and electrolytic capacitor 如碧空株式会社 2004-09-15 — — CN claimed
EP-1437749-A1 ELECTROLYTE SOLUTION FOR DRIVING ELECTROLYTIC CAPACITOR AND ELECTROLYTIC CAPACITOR Rubycon Corporation (JP) 2004-07-14 — — EP claimed
EP-0970689-B1 Make-up product with a photochromic pigment and a UV-filter and its uses OREAL (FR) 2002-09-18 — — EP claimed
US-6080415-A SEPARATE PACKAGES OF A FIRST COMPONENT OF A COSMETIC MEDIUM CONTAINING A PHOTOCHROMIC COLORING AGENT WHICH PRODUCES A COLOR IN THE PRESENCE OF ULTRAVIOLET RADIATION AND THE SECOND A SUNSCREENING AGENT; IMPROVED COLORANT EFFECT; PATTERNS L'OREAL (FR) 2000-06-27 — — US claimed
EP-0970689-A2 Make-up product with a photochromic pigment and a UV-filter and its uses L'OREAL (FR) 2000-01-12 — — EP claimed
CN-106047834-B A kind of Aspergillus usamii epoxide hydrolase mutant that enantioselectivity improves 江南大学 2019-11-08 — — CN disclosed
CN-109609479-A A kind of Aspergillus usamii epoxide hydrolase mutant that enantioselectivity improves 江南大学 2019-04-12 — — CN disclosed
US-3996052-A Phototropic compounds as acid catalyst in photopolymerizing process AMERICAN CAN COMPANY (US) 1976-12-07 — — US disclosed
US-3949143-A Epoxy resin coatings cured with phototropic aromatic nitro compounds AMERICAN CAN COMPANY (US) 1976-04-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050175562-A1 crosslinked organopolysiloxane having dimethylvinylsiloxy end groups and a methylhydropolysiloxane having trimethylsiloxy end groups; water, oil, water soluble sovlent as liquid binder; and goniochromatic / photochromic or fluorescent coloring agents; cosmetic MICA, MITF, CUTA ALDH1A1 3297/4885KDM4E 1619/4885TSHR 3787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.