Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.59 |
| ▸ | CA2 | P00918 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.41 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.39 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4602822 | 1.00 | ALDH1A1 (0.68) | ALDH1A1KMT2ATAAR1CA2MAPT | |
| SCHEMBL4602421 | 0.88 | ALDH1A1 (0.63) | ALDH1A1KMT2ATAAR1CA2MAPT | |
| SCHEMBL4602418 | 0.88 | ALDH1A1 (0.63) | ALDH1A1KMT2ATAAR1CA2MAPT | |
| SCHEMBL13310215 | 0.81 | ALDH1A1 (0.56) | ALDH1A1KMT2ATAAR1CA2MAPT | |
| SCHEMBL11294847 | 0.81 | KMT2A (0.46) | ALDH1A1KMT2ATAAR1CA2MAPT | |
| SCHEMBL13299411 | 0.81 | SMN1; SMN2 (0.52) | ALDH1A1KMT2ATAAR1CA2CA1 | |
| SCHEMBL11294849 | 0.81 | KMT2A (0.46) | ALDH1A1KMT2ATAAR1CA2MAPT | |
| SCHEMBL12389205 | 0.81 | ALDH1A1 (1.00) | ALDH1A1KMT2ATAAR1CA2MAPT | |
| SCHEMBL474203 | 0.80 | CA2 (0.53) | ALDH1A1KMT2ATAAR1CA2CA1 | |
| SCHEMBL474202 | 0.80 | CA2 (0.53) | ALDH1A1KMT2ATAAR1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1194633-B1 | AGENT FOR COLORING FIBERS AND METHOD FOR TEMPORARILY COLORING FIBERS | WELLA AG (DE) | 2008-04-30 | — | — | EP | claimed |
| US-7056348-B2 | 5-aryl-1,3,3-trimethyl-2-methylene-indoline derivatives and salts thereof, methods for the production and use of said compounds for the temporary coloration of fibers | WELLA AG (DE) | 2006-06-06 | — | — | US | claimed |
| EP-1404289-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | Wella Aktiengesellschaft (DE) | 2004-04-07 | — | — | EP | claimed |
| US-6669739-B2 | Agent for coloring fibers and method for temporarily coloring fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2003-12-30 | — | — | US | claimed |
| US-20030213071-A1 | 5-Aryl-1.3.3.-trimethyl-2-methylene-indoline derivatives and salts thereof, methods for the production and use of said compounds for the temporary coloration of fibres | Wella GmbH (DE) | 2003-11-20 | — | — | US | claimed |
| US-20030196281-A1 | 1-benzopyrane-derivatives and colouring agents containing the salts thereof | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | US | claimed |
| EP-1280773-A1 | 5-ARYL-1.3.3.-TRIMETHYL-2-METHYLENE-INDOLINE DERIVATIVES AND SALTS THEREOF, METHODS FOR THE PRODUCTION AND USE OF SAID COMPOUNDS FOR THE TEMPORARY COLORATION OF FIBRES | Wella Aktiengesellschaft (DE) | 2003-02-05 | — | — | EP | claimed |
| WO-2003000214-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | claimed |
| US-20020172651-A1 | Agent for coloring fibers and method for temporarily coloring fibers | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2002-11-21 | — | — | US | claimed |
| WO-2002085854-A1 | 5-ARYL-1.3.3.-TRIMETHYL-2-METHYLENE-INDOLINE DERIVATIVES AND SALTS THEREOF, METHODS FOR THE PRODUCTION AND USE OF SAID COMPOUNDS FOR THE TEMPORARY COLORATION OF FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-31 | — | — | WO | claimed |
| EP-1194633-A1 | AGENT FOR COLORING FIBERS AND METHOD FOR TEMPORARILY COLORING FIBERS | Wella Aktiengesellschaft (DE) | 2002-04-10 | — | — | EP | claimed |
| WO-2001086057-A1 | AGENT FOR COLORING FIBERS AND METHOD FOR TEMPORARILY COLORING FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2001-11-15 | — | — | WO | claimed |
| EP-1194633-B1 | AGENT FOR COLORING FIBERS AND METHOD FOR TEMPORARILY COLORING FIBERS | WELLA AG (DE) | 2008-04-30 | — | — | EP | disclosed |
| US-7300472-B2 | Agents for coloring fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-11-27 | — | — | US | disclosed |
| US-20070000074-A1 | Agents for coloring fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2007-01-04 | — | — | US | disclosed |
| EP-1534227-B1 | AGENTS USED FOR DYEING KERATINOUS FIBERS | HENKEL KGAA (DE) | 2006-12-27 | — | — | EP | disclosed |
| US-20020172651-A1 | Agent for coloring fibers and method for temporarily coloring fibers | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2002-11-21 | — | — | US | disclosed |
| WO-2002085854-A1 | 5-ARYL-1.3.3.-TRIMETHYL-2-METHYLENE-INDOLINE DERIVATIVES AND SALTS THEREOF, METHODS FOR THE PRODUCTION AND USE OF SAID COMPOUNDS FOR THE TEMPORARY COLORATION OF FIBRES | WELLA AKTIENGESELLSCHAFT (DE) | 2002-10-31 | — | — | WO | disclosed |
| EP-1194633-A1 | AGENT FOR COLORING FIBERS AND METHOD FOR TEMPORARILY COLORING FIBERS | Wella Aktiengesellschaft (DE) | 2002-04-10 | — | — | EP | disclosed |
| WO-2001086057-A1 | AGENT FOR COLORING FIBERS AND METHOD FOR TEMPORARILY COLORING FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2001-11-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030213071-A1 | 5-Aryl-1.3.3.-trimethyl-2-methylene-indoline derivatives and salts thereof, methods for the production and use of said compounds for the temporary coloration of fibres | INMT, KRT18, IPO5 | ALDH1A1 440/4885KMT2A 648/4885TAAR1 93/4885 |
| US-20030196281-A1 | 1-benzopyrane-derivatives and colouring agents containing the salts thereof | KRT18, COL2A1, PHB1 | ALDH1A1 9/4885KMT2A 1669/4885TAAR1 2764/4885 |
| US-20070000074-A1 | Agents for coloring fibers containing keratin | KRT18, COL1A1, CYC1 | ALDH1A1 780/4885KMT2A 1075/4885TAAR1 2266/4885 |
| US-20020172651-A1 | Agent for coloring fibers and method for temporarily coloring fibers | ENO1, H1-5, H1-2 | ALDH1A1 62/4885KMT2A 943/4885TAAR1 207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.