Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4946413 | 0.85 | TRPA1 (0.36) | TRPA1TRPM8EPHX1 | |
| SCHEMBL4951227 | 0.83 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL9881201 | 0.78 | TSHR (0.33) | — | |
| SCHEMBL98088 | 0.76 | — | — | |
| SCHEMBL15178896 | 0.70 | EPHX1 (0.33) | TRPA1TRPM8EPHX1 | |
| SCHEMBL96535 | 0.68 | ALDH1A1 (0.50) | TRPA1TRPM8EPHX1 | |
| SCHEMBL2633946 | 0.68 | ALDH1A1 (0.50) | TRPA1TRPM8EPHX1 | |
| SCHEMBL16377090 | 0.67 | EPHX1 (0.33) | TRPA1TRPM8EPHX1 | |
| SCHEMBL28383550 | 0.67 | EPHX1 (0.33) | TRPA1TRPM8EPHX1 | |
| SCHEMBL22744632 | 0.67 | TRPM8 (0.46) | TRPA1TRPM8EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130165506-A1 | PULEGANIC ACID INSECT REPELLENT | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-27 | — | — | US | disclosed |
| CN-101316811-A | Puleganic amides as insect repellents | DU PONT (US) | 2008-12-03 | — | — | CN | disclosed |
| US-7435851-B2 | Puleganic amides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-10-14 | — | — | US | disclosed |
| EP-1940778-A1 | PULEGANIC AMIDES AS INSECT REPELLANTS | E.I.Du pont de nemours and company (US) | 2008-07-09 | — | — | EP | disclosed |
| EP-1940226-A1 | PULEGANIC ACID INSECT REPELLENTS | E.I.Du pont de nemours and company (US) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007041306-A1 | PULEGANIC ACID INSECT REPELLENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-04-12 | — | — | WO | disclosed |
| WO-2007041307-A1 | PULEGANIC AMIDES AS INSECT REPELLANTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-04-12 | — | — | WO | disclosed |
| US-20070077262-A1 | Puleganic acid insect repellents | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-04-05 | — | — | US | disclosed |
| US-20070077263-A1 | N-Substituted or N,N-disubstituted-2-isopropyl-5-methylcyclopentanecarboxamides, e.g., N,N-diethyl- or N-benzyl-; useful as a topical treatment for skin, such as a repellant for insects and arthropods | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165506-A1 | PULEGANIC ACID INSECT REPELLENT | CUTA, PPT1, PCCA | TRPA1 75/4885TRPM8 1766/4885EPHX1 1693/4885 |
| US-20070077263-A1 | N-Substituted or N,N-disubstituted-2-isopropyl-5-methylcyclopentanecarboxamides, e.g., N,N-diethyl- or N-benzyl-; useful as a topical treatment for skin, such as a repellant for insects and arthropods | CUTA, PNN, NAPEPLD | TRPA1 617/4885TRPM8 2200/4885EPHX1 1023/4885 |
| US-20070077262-A1 | Puleganic acid insect repellents | CUTA, PPT1, PCCA | TRPA1 55/4885TRPM8 1459/4885EPHX1 1669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.