Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227590 | 0.81 | METAP2 (0.57) | METAP2KDM4EKMT2AMEN1PLAU | |
| SCHEMBL4626576 | 0.78 | MEN1 (0.56) | METAP2KDM4EKMT2AMEN1ALDH1A1 | |
| SCHEMBL4624601 | 0.77 | KMT2A (0.48) | METAP2KDM4EKMT2AMEN1PLAU | |
| SCHEMBL1043719 | 0.74 | METAP2 (0.58) | METAP2KDM4EKMT2AMEN1PLAU | |
| SCHEMBL2095245 | 0.73 | AGTR1 (0.58) | KMT2AMEN1AGTR1NPC1RAB9A | |
| SCHEMBL4624293 | 0.73 | KDM4E (0.49) | METAP2KDM4EKMT2AMEN1PLAU | |
| 8-Hydroxy Quinaldine SCHEMBL2434060 | 0.73 | METAP2 (0.72) | METAP2KDM4EKMT2AMEN1PLAU | |
| SCHEMBL30457998 | 0.73 | METAP2 (0.56) | METAP2KDM4EKMT2AMEN1PLAU | |
| SCHEMBL29040602 | 0.73 | METAP2 (0.56) | METAP2KDM4EKMT2AMEN1PLAU | |
| SCHEMBL29040599 | 0.73 | METAP2 (0.56) | METAP2KDM4EKMT2AMEN1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080306191-A1 | Polyisocyanate and Waterglass Based Hybrid Resins, Composites Containing Them and Process to Produce Them | POLINVENT KFT. (HU) | 2008-12-11 | — | — | US | disclosed |
| EP-1791886-B1 | POLYISOCYANATE AND WATERGLASS BASED HYBRID RESINS, COMPOSITES CONTAINING THEM AND PROCESS TO PRODUCE THEM | POLINVENT KFT (HU) | 2008-07-16 | — | — | EP | disclosed |